Mammalian cell and tissue imaging using Raman and coherent Raman microscopy

AA Fung, L Shi - Wiley Interdisciplinary Reviews: Systems …, 2020 - Wiley Online Library
… makes Raman spectroscopy an excellent tool for biological … metabolically active but not
proliferating cells. They revealed … and pancreatic cancer PANC1 cell lines. They observed that …

Raman spectroscopy and regenerative medicine: a review

KJI Ember, MA Hoeve, SL McAughtrie… - NPJ Regenerative …, 2017 - nature.com
… ”) offers the capacity to biochemically assess cell and tissue … The uncontrolled proliferation
associated with cancers is … organs, tissue sections, cell culture and biological fluids eg, serum, …

Raman and infrared spectroscopy reveal that proliferating and quiescent human fibroblast cells age by biochemically similar but not identical processes

K Eberhardt, C Matthäus, S Marthandan, S Diekmann… - PLoS …, 2018 - journals.plos.org
Raman spectra of each single cell were averaged resulting … not only to spectra of proliferating
cells, confirming earlier … , we detected differences in the Raman and FT-IR spectra of …

Applications of Raman spectroscopy in the development of cell therapies: state of the art and future perspectives

S Rangan, HG Schulze, MZ Vardaki, MW Blades… - Analyst, 2020 - pubs.rsc.org
… for mammalian cell culture therapeutic protein or cell manufacturing. … sample-based
biochemical methods. Herein, we survey … As stem cells become less proliferative when …

Identification of four similar cell culture media according to their glucose, glutamine, and pyruvate content by handheld Raman spectroscopy

K Echeverría-Altamar, BB Alvarado-Hernandez… - Pharmaceutical …, 2023 - Springer
… could decrease cell proliferation and production of growth … on the sample simultaneously
and are detected by the charge-… the spectra was related to the heterogeneity of the cell culture

Ramanomics: new omics disciplines using micro Raman spectrometry with biomolecular component analysis for molecular profiling of biological structures

AN Kuzmin, A Pliss, PN Prasad - Biosensors, 2017 - mdpi.com
… The good quality of spectral modeling in different cell lines … high, resulting in distortion of the
Raman spectrum even after … variation in the Raman spectra can be detected in the different …

Detection of early osteogenic commitment in primary cells using Raman spectroscopy

SJ Smith, R Emery, A Pitsillides, CE Clarkin, S Mahajan - Analyst, 2017 - pubs.rsc.org
… specific detection of proliferation and differentiation changes … 20 spectra were acquired
for a cell culture sample. Overall … in detail, we present the results of biological techniques …

Different phases of breast cancer cells: Raman study of immortalized, transformed, and invasive cells

D Chaturvedi, SA Balaji, VK Bn, F Ariese, S Umapathy… - Biosensors, 2016 - mdpi.com
… to identify these characteristics using Raman spectroscopy. … the biochemical profiles of the
various cell lines representing … membrane formation during rapid cell proliferation [64]. This …

Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapy

C Ma, L Zhang, T He, H Cao, X Ren, C Ma… - Stem Cell Research & …, 2021 - Springer
lead to the proliferation of PHH in vitro, and the proliferating … The cell culture medium was
changed every 3 days. After 7 … changes of biochemical molecules in the process of somatic …

Raman microscopy based sensing of leukemia cells: A review

S Managò, G Zito, AC De Luca - Optics & Laser Technology, 2018 - Elsevier
… of a Raman spectroscopy-based protocol for a complete biochemical and morphological
analysis of leukemia cells. … They are characterized by uncontrolled and rapid cell proliferation of …