… Pemetrexed with Docetaxel monotherapy in elderly patients with advanced nonsquamous non–small cell lung cancer: a phase 3 randomized clinical trial

I Okamoto, H Nokihara, S Nomura, S Niho… - JAMA …, 2020 - jamanetwork.com
… OS between the 2 groups, although carboplatin-pemetrexed treatment showed a statistically
significant PFS advantage over single-agent docetaxel. A substantial proportion of patients …

Randomized phase 2 trial of pemetrexed, pemetrexed/bevacizumab, and pemetrexed/carboplatin/bevacizumab in patients with stage IIIB/IV non–small cell lung …

…, DL Shipley, MK Hagan, DS Thompson, HA Burris III… - Cancer, 2018 - Wiley Online Library
… During the time our trial was being conducted, results were reported from an ECOG
randomized phase 3 trial comparing single-agent pemetrexed with pemetrexed and carboplatin in …

Randomized phase III trial comparing switch-maintenance pemetrexed with observation followed by pemetrexed at progression in advanced NSCLC

TO Halvorsen, K Stokke, KT Killingberg, SX Raj… - Acta …, 2020 - Taylor & Francis
… years, where maintenance pemetrexed was well tolerated … phase III study of elderly patients
(age 75–88) in which advanced NSCLC patients who received carboplatin plus pemetrexed

[HTML][HTML] Efficacy and safety of first-line pemetrexed plus carboplatin followed by single-agent pemetrexed maintenance in elderly Chinese patients with non-squamous …

X Zhao, H Yu, J Zhao, X Wu, S Sun, Z Luo, H Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… Chemotherapy with pemetrexed plus carboplatin followed by pemetrexed maintenance therapy
is … This phase II clinical study investigated the efficacy and safety of this regimen in older …

A phase II study of pemetrexed plus carboplatin followed by maintenance pemetrexed as first-line chemotherapy for elderly patients with advanced non-squamous …

M Tamiya, A Tamiya, H Kaneda, K Nakagawa, K Yoh… - Medical Oncology, 2016 - Springer
… (CBDCA, area under the curve = 5) plus pemetrexed (PEM, 500 … We conducted a multicenter
phase II trial to evaluate the efficacy … Currently, single-agent chemotherapy is used as the …

Pemetrexed clinical studies in performance status 2 patients with non-small cell lung cancer

R Zinner, C Visseren-Grul… - … journal of oncology, 2016 - spandidos-publications.com
… At the time of this study, single-agent docetaxel had already … Single agent Alimta in poor
performance status in non-small … Randomized phase II trial of paclitaxel plus carboplatin or …

[HTML][HTML] Maintenance therapy with pemetrexed and bevacizumab versus pemetrexed monotherapy after induction therapy with carboplatin, pemetrexed, and …

M Karayama, N Inui, T Fujisawa, N Enomoto… - European Journal of …, 2016 - Elsevier
Single agent maintenance therapy is widely accepted for advanced non-… randomised
phase II study, we evaluated the efficacy and safety of maintenance therapy with pemetrexed

[HTML][HTML] Phase III study of gefitinib or pemetrexed with carboplatin in EGFR-mutated advanced lung adenocarcinoma

VM Patil, V Noronha, A Joshi, AB Choughule… - ESMO open, 2017 - Elsevier
… standard adenocarcinoma regimen (pemetrexed carboplatin induction followed by maintenance
pemetrexed) and patients from Indian subcontinent. Hence, this study was carried out in …

A randomized, double‐blinded, Phase II trial of Carboplatin and Pemetrexed with or without Apatorsen (OGX‐427) in patients with previously untreated stage IV non …

…, J Stilwill, T Mekhail, C Jacobs, HA Burris III… - The …, 2019 - academic.oup.com
… This randomized phase II trial was undertaken to evaluate the efficacy and safety of apatorsen
when added to a standard carboplatin/pemetrexed regimen in the first‐line treatment of …

[HTML][HTML] A randomized, open-label, phase II study comparing pemetrexed plus cisplatin followed by maintenance pemetrexed versus pemetrexed alone in patients …

KH Yoo, SJ Lee, J Cho, KH Lee, KU Park… - Cancer Research and …, 2019 - ncbi.nlm.nih.gov
… -center randomized phase II trial to compare the clinical outcomes between pemetrexed
plus … Our results suggest that single-agent pemetrexed might be another treatment option for …