… latent CMV may be detected and amplified in leukocyte… relevant CMV threshold that highly
predicts the development of CMV … Antiviral therapy selects for CMV gene mutations that confer …

… on samples obtained from 28 letermovir-treated patients who had … in vivo cytomegalovirus
carrying the UL56 mutation C325Y, … to reduce the incidence of mutations and side effects. In …

… drug resistance mutations (DRMs) until CMV pneumonitis … develop by intrapatient emergence
of CMV variants resistant … A–C, Patient values of absolute leukocyte, lymphocyte, and …

… It is widely acknowledged that HCMV can spread systemically via leucocytes, a … mutations
[159,160]—ie new mutations occur every time the virus infects a new host, thereby giving rise …

… characterization of CMV resistance mutations in allogeneic … the rapid emergence of resistance
to GCV in one of the patients, only … Regarding the percentage of patients with virological …

… in the development and/or severity of inflammatory cardiovascular diseases and to the … or
by eliminating leukocytes from the transfused blood reduces the transfusion-acquired HCMV …

… mutation, was significantly higher among patients with CMV … 8 comparing the incidence of
CMV infection in patients with … acquired and hereditary predisposing factors in patients with …

… with the development of drug-resistant CMV infection. … until a negative plasma CMV DNA
test result was obtained. … transfusion of CMV-specific cytotoxic T lymphocytes (CTLs). These …

… the development of resistance, due to the mutation of UL97 [13, 28], and the suppression of
hematopoi-esis, especially leukocytes [… marrow obtained from CMV seropositive donors [59]. …

… the most prevalence of point mutations in UL54 in Americas … chances for virus to acquire
resistance-related mutations [68,… that the development of resistance in CMV should be verified …