… as products of reactions with peroxynitrite [115]. However, the outcome concerning
melatonin nitration by peroxynitrite remained rather modest. One study reported the absence of …

… of NO, reducing peroxynitrite formation and protecting from … part, by modulating the NO/NOS
system response. With this aim, we … This mechanism also implies that, under hypoxia, HIF-1α …

… The RAF mechanism has been identified as important for the reactions of melatonin not only
with OH,376, 383 but also with OOCCl 3 376 and α-hydroxyethyl radicals.384 On the other …

… research. Objective: This review summarizes the chemical insights concerning the antioxidant
capacity (AOC) of melatonin … so far it can be stated that melatonin and related compounds …

… Electron donation is the principal mechanism by which melatonin detoxifies the … Melatonin
also scavenges peroxynitrite, but it is difficult to discriminate direct reactions with peroxynitrite …

… , AMFK, and AMK can scavenge NO and peroxynitrite. The highest reactivity towards radical
nitrogen … The question about most preferred reaction mechanism of melatonin still remains …

… work mechanism remains to be further clarified. In this study, it was shown that peroxynitrite
… had the best response according to our result) melatonin exhibited significant improvements …

… /Haber–Weiss reactions; in doing so, melatonin reduces the … , that is, nitric oxide and the
peroxynitrite anion, both of which … actions are well described and mechanistically defined,218, …

… subunits exposed to peroxynitrite were damaged, but protection by melatonin required very
… by a mechanism involving a mitochondrial cytochrome P 450 subform [14]. This response is …

… molecule related to NO was not analyzed in this study. Melatonin is known to react with
peroxynitrite, and it could be expected that in a cellular environment, this would be a mechanism …