… , (4) less reactogenicity compared with use of full-dose diphtheria vaccine, potentially improving
the … evidence on immunogenicity and safety of Td vaccine use in 4–7 year old children. …

… The most prominent feature of this vaccine is its relatively high reactogenicity. … assessment
of DTwP immunogenicity is highly needed. … For such vaccines, immunogenicity studies and …

… found to have a good tolerability profile and to be immunogenic in all indicated age groups.
… interference and impact on vaccine reactogenicity and safety. Immunologic interference is of …

… reduced the morbidity and mortality associated with pertussis. Because of reports on the
induction of adverse reactions, less-reactogenic acellular … on their aforementioned immunogenic …

… The composition, safety, and immunogenicity of various DTaP vaccines were … reduced
endotoxin content to be less reactogenic, outer membrane vesicles–based vaccines, and acellular …

… the continuous discovery of immunogenic epitopes. Bacteria possess a variety of antigens
whose immunogenic potential is often unknown, and it is unclear which antigen can elicit a …

… regarding the response to pertussis antigens, the latter response remained robust and is
unlikely to be clinically relevant. Overall, the safety, reactogenicity, and immunogenicity data …

… to the severity of reactogenic responses associated with it. This reactogenicity continues to
be a … burnetii vaccines, our knowledge of immunogenicity and reactogenicity in C. burnetii …

… period; reactogenicity events were solicited through day 42. … that antigen delivery was limited
by specific characteristics of human adult skin. Indeed, human skin has lower water content, …

… , widespread vaccination of young children has reduced the incidence of pertussis. However,
due to the high reactogenicity of wPvs, acellular pertussis vaccines (aPv) were developed …