Fibroblasts: the unknown sentinels eliciting immune responses against microorganisms

LA Bautista-Hernández, JL Gómez-Olivares… - European Journal of …, 2017 - akjournals.com
immune repertoire in responding to different microbial agents. In this review, we will cover
the immunologic … an important role in recognizing microbial components from bacteria, fungi, …

The critical role of toll-like receptors—from microbial recognition to autoimmunity: a comprehensive review

MJ Jiménez-Dalmaroni, ME Gerswhin… - Autoimmunity …, 2016 - Elsevier
… or microbial ligands and accessory molecules determine the activating or inhibitory responses.
Herein, we review the TLR-mediated activation of innate immune cells in their activation

Multi-receptor detection of individual bacterial products by the innate immune system

KJ Kieser, JC Kagan - Nature Reviews Immunology, 2017 - nature.com
… signatures represents a new frontier in the study of innate immunity, and is the focus of …
recognized by at least two and as many as four different receptors of the innate immune system. …

Peptidoglycan recognition by the innate immune system

AJ Wolf, DM Underhill - Nature Reviews Immunology, 2018 - nature.com
… peptidoglycans are recognized by the mammalian innate immune system and … recognition
systems in homeostatic regulation of immunity and metabolism. Peptidoglycan recognition is …

Pattern recognition receptors in health and diseases

D Li, M Wu - Signal transduction and targeted therapy, 2021 - nature.com
… We focus on the different domains and ligand recognition mechanisms between PRRs, …
promote the study of the role of the innate immune system in related diseases and even tumors. …

Pattern recognition receptors in the crustacean immune response against bacterial infections

JL Sánchez-Salgado, MA Pereyra, JJ Alpuche-Osorno… - Aquaculture, 2021 - Elsevier
… Identification of multiple PRRs families participate in the activation of immune response. …
bacteria to better understand how they activate humoral and cellular immune responses. …

Not by structures alone: Can the immune system recognize microbial functions?

GP Greslehner - Studies in History and Philosophy of Science Part C …, 2020 - Elsevier
… also by a biological system such as the immune system. In … immunological recognition of
microbial functions discussed in this paper sheds new light on the plurality of notions of function

The many roles of galectin‐3, a multifaceted molecule, in innate immune responses against pathogens

L Díaz-Alvarez, E Ortega - Mediators of inflammation, 2017 - Wiley Online Library
immune response against invading pathogens. Galectin-3 has been proposed to function
not only as a pattern-recognition … of immune responses against pathogenic microorganisms. …

Recognition of endogenous nucleic acids by the innate immune system

A Roers, B Hiller, V Hornung - Immunity, 2016 - cell.com
… Our understanding of self- versus non-self-recognition by the innate immune system has
come a long way since the seminal concept paper on innate immune recognition by Charles …

Friendly fire: recognition of self by the innate immune system

V Hornung, MM Gaidt - Current Opinion in Immunology, 2024 - Elsevier
… that activate Toll-like receptors (TLRs) and, by extension, other PRRs. Recognizing PTI as
just one crucial aspect of innate immune … of sterile immune responses by incorporating recent …