[HTML][HTML] Endogenous SO2-dependent Smad3 redox modification controls vascular remodeling

Y Huang, Z Li, L Zhang, H Tang, H Zhang, C Wang… - Redox biology, 2021 - Elsevier
… protein cysteine residues to a sulfenic acid group, aka cysteine … Herein, the identification of
a redox-sensitive cysteine C64 in … The above studies indicate that the normal cardiovascular

Redox-dependent regulation of sulfur metabolism in biomolecules: implications for cardiovascular health

RK Mistry, AC Brewer - Antioxidants & redox signaling, 2019 - liebertpub.com
… This property underlies the catalytic and redox-sensitive … formation of sulfenic acid, sulfinic
acid, and sulfonic acid states as … expression of GCLC (and other known Nrf2-regulated genes…

Biological chemistry and functionality of protein sulfenic acids and related thiol modifications

NO Devarie-Baez, EI Silva Lopez… - Free radical …, 2016 - Taylor & Francis
… S100A1 and S100B are two examples of proteins with redox-sensitive C-… cardiovascular
and neurological diseases to diabetes, aging and cancer. With several of the redox-regulated

[HTML][HTML] S-glutathionylation, friend or foe in cardiovascular health and disease

NA Rashdan, B Shrestha, CB Pattillo - Redox Biology, 2020 - Elsevier
… ) and can be directly regulated by the local redox state of the … in the form of sulfinic and
sulfonic acids resulting in protein … for the protection of redox sensitive cysteines from deleterious …

[HTML][HTML] Redox regulation by protein S-glutathionylation: from molecular mechanisms to implications in health and disease

A Musaogullari, YC Chai - International journal of molecular sciences, 2020 - mdpi.com
… , sulfenic acids are subject to further oxidation to sulfinic acid … their redox-sensitive active
sites in the reduced state [48]. … in the regulation of cardiac dynamics is cardiac myosin binding …

Redox modification of caveolar proteins in the cardiovascular system-role in cellular signalling and disease

KJ Bubb, AB Birgisdottir, O Tang, T Hansen… - Free Radical Biology …, 2017 - Elsevier
… is critical in regulating cardiovascular functions like cardiomyocyte … and in rat hearts exposed
to oxidative stress sulfenic acid adducts … of redox-sensitive proteins and therefore functional …

Redox control of vascular biology

M Obradovic, M Essack, S Zafirovic… - Biofactors, 2020 - Wiley Online Library
… core aspects of redox biology, cardiovascular physiology, and … These modifications (except
sulfonic acid and to a lower … kinase, required for redox-sensitive signal transduction initiated …

[HTML][HTML] Thiol-based redox-active proteins as cardioprotective therapeutic agents in cardiovascular diseases

I Andreadou, P Efentakis, K Frenis, A Daiber… - Basic Research in …, 2021 - Springer
… induce thiol modifications, regulate redox signaling involved … by overoxidation to the
sulfinic/sulfonic acid product by H 2 O … membrane via activation of redox-sensitive protein kinase C …

[HTML][HTML] Redox regulation via glutaredoxin-1 and protein S-glutathionylation

R Matsui, B Ferran, A Oh, D Croteau… - Antioxidants & Redox …, 2020 - el.liebertpub.com
… One of these stages requires oxidation of cysteine to sulfenic acid, … (B) Redox-sensitive
proteins contain exposed and … with the cardiac muscle LIM protein and negatively regulates

Endothelial cell redox regulation of ischemic angiogenesis

RA Cohen, CE Murdoch, Y Watanabe… - … of cardiovascular …, 2016 - journals.lww.com
modifications, chlorotyrosine, and cysteine sulfonic acid (-SO 3 H) … Our studies show
that Glrx1 regulates hindlimb ischemia, … In addition, the mouse in which 50% of the redox-sensitive