… In animal and in vitro models of human small intestinal enteroids, NHE3 inhibition increases
… reduced phosphate absorption and facilitated a 50% reduction in phosphate binder dose […

… mainly based on reducing phosphorus in the diet and with phosphate (P) binders. In this in
… The aim of our in vitro study is the comparison of phosphate binding activity at pH 3 and 7 …

… Based on the results regarding the reduced phosphate binding capacity of the phosphate
binders … , it was indicated that the results obtained in vitro were generally well reflected in vivo. …

… Overall, calcium acetate reduced phosphate absorption by an average of 174 mg (26.8
mg per dose), but the observed binding efficacy ranged from 15.0 to 36.1 mg per dose. …

… Theoretically, serum phosphorus levels can be controlled in dialysis patients by interventions
aimed at reducing gastrointestinal (GI) absorption and/or enhancing dialytic removal of …

… is reduced along with phosphorus excretion from the kidney, resulting in the accumulation of
absorbed dietary phosphorus … expected phosphate-binding capacity (theoretical phosphate-…

… Data are theoretical to simplify the figures and improve the fits, and axes show arbitrary …
The drug also inhibited Pi absorption in rat in vivo, it reduced renal Pi excretion in the same …

… While both maneuvers may theoretically modulate the gut … -dialysis CKD patients and in
vitro binding to microbiota-derived … reducing dietary phosphate absorption, phosphate binders …

… hyperphosphatemia aims to reduce intestinal phosphate absorption by combining dietary …
calculated using the complete additivity of probability theory based on the observed effect of …

… Since the mineral load associated with CPP-II should theoretically be a product of both … in
vitro, we hypothesised that lowering serum CPPs with high-dose SO should decrease the pro-…