… using decision-analysis modeling demonstrated that reflex-testing pathways for … Lynch
syndrome screening program, its implementation, and how the program came to be in its current …

… , the uptake of reflex-testing programs within health systems has … of a provincial program for
reflex testing in Ontario, Canada. … program for reflex screening in Ontario was reviewed, and …

… Lynch syndrome (LS) screening can significantly reduce cancer morbidity and mortality in
mutation carriers. Our aim was to identify cost-effective LS screening programs that … review, we …

… Providers supported a reflex-testing program because of the current lack of coordinated …
review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome …

… Reflex testing for Lynch syndrome using MMR immunohistochemistry and MLH1 methylation
testing was cost-effective versus no testing, costing £… Furthermore, programmes testing all …

… LS screening or diagnosis), we performed manual chart reviews to abstract information on
the details of tumor screening (eg, MSI, IHC) and germline testing, if available… reflex testing for …

… of Lynch syndrome (LS) recommend molecular screening of colorectal cancers (CRCs) to
identify patients for germline mismatch repair (MMR) gene testing. … LS screening programs has …

… not screened by IHC only had a biopsy sample available. … an abnormal result after reflex
testing and were referred for … included in our analysis, the UTS program did not identify any …

… Flow chart summarising the results of reflex Lynch syndrome screening at … analysis was
performed on all cases with MSH2 loss and should not be a source of error. Also, we reviewed …

… We evaluated compliance to universal reflex testing and for … Univariable analysis was also
performed for referral for … specimen testing was for the reflex program; multivariable analysis …