… , multilayered epigenetic event essential for mouse development [6], … mice and
humans [7], [8], [9]. XCI is not a permanent state, as it is reversed in the mouse embryo by X-chromosome …

… mouse and human early development. During female mouse pre-implantation development
(top), X chromosome … of human X chromosome inactivation during early development, …

… Similarly, deletion of the region including DXZ4 on the mouse X chromosome prior to XCI
resulted in a massive reorganization of the mutant Xi upon differentiation and XCI with fusion of …

… chromosome-wide inactivation and its proper … regulation of X inactive-specific transcript
(XIST), a major factor of XCI, in the context of mouse and human early embryonic development. …

… of X chromosome inactivation, discuss the relationship between X chromosome inactivation
… Related studies have revealed that the loss of Xist in mouse hematopoietic cells leads to the …

… We have put these new findings in perspective using previous data obtained in human (and
mouse) embryos. In addition, there is an ongoing discussion whether or not hPSC lines …

… Additionally, the mouse X chromosome is acrocentric whereas the human X is … might reduce
the strength of the X inactivation signal on the human short arm. Other species have differing …

… current understanding of X-chromosome dynamics during human development and comment
… knowledge of X-chromosome regulation thus far is mainly based on studies in mice, which …

… due to the inactivation of one or other X chromosome early in embryonic development’ (Disteche
and Berletch 2015). This reasoning was proven to be accurate, first based on mice, and …

… mouse are not conserved in human. Here, we will discuss recent advances in understanding
… control of X-chromosome dosage compensation in early human embryonic development …