Cell adhesion molecules in normal and malignant hematopoiesis: from bench to bedside

JP Levesque, IG Winkler - Current Stem Cell Reports, 2016 - Springer
… and regulate HSPC fate during hematopoiesis. We review how malignant hematopoietic cells
utilize adhesive … Finally, we review how these adhesive interactions can be therapeutically …

Fibronectin and its receptors in hematopoiesis

F Wirth, A Lubosch, S Hamelmann, IA Nakchbandi - Cells, 2020 - mdpi.com
… of integrins in hematopoiesis followed by a discussion of the effects of fibronectin and
fibronectin-binding receptors on … The differentiation of hematopoietic stem cells is tightly regulated, …

Physiological cues involved in the regulation of adhesion mechanisms in hematopoietic stem cell fate decision

R Kulkarni, V Kale - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
… the adhesion molecules involved in the regulation of HSCs, … known to initiate specific
adhesive interactions of HSCs with … the adhesion mechanisms operative in hematopoietic system…

[HTML][HTML] Integrins modulate extracellular matrix organization to control cell signaling during hematopoiesis

RJ Khadilkar, KYL Ho, B Venkatesh, G Tanentzapf - Current Biology, 2020 - cell.com
… that control hematopoiesis remains to be resolved. Here, we show … integrins play a key role
during fly hematopoiesis in regulating cell signals that control the behavior of hematopoietic

Adhesion receptors involved in HSC and early-B cell interactions with bone marrow microenvironment

M De Grandis, AC Lhoumeau, SJC Mancini… - Cellular and molecular …, 2016 - Springer
… and acting at specific stage of differentiation to regulate hematopoietic homeostasis. Here,
we review recent data on adhesion mechanisms involved in HSCs and B cell progenitors …

Adhesion molecules involved in stem cell niche retention during normal haematopoiesis and in acute myeloid leukaemia

JMP Grenier, C Testut, C Fauriat, SJC Mancini… - Frontiers in …, 2021 - frontiersin.org
adhesion molecules that regulate HSC quiescence, proliferation and commitment. During
to study the function of adhesion molecules in HSC’s homeostasis regulation. Since the 90’s, …

Mechanoregulation in hematopoiesis and hematologic disorders

PD Horton, S Dumbali, PL Wenzel - Current Stem Cell Reports, 2020 - Springer
Integrins The integrin family of cell surface receptors is transmembrane heterodimeric receptors
… Signaling through integrins is regulated by conformational change and their activation …

Adhesion GPCRs in regulating immune responses and inflammation

HH Lin, CC Hsiao, C Pabst, J Hébert… - Advances in …, 2017 - Elsevier
… in hematopoietic stem, progenitor, or mature cells, where they define distinct cellular populations.
Recent studies have demonstrated roles of aGPCR in the control of … in the regulation of …

Oncogenic deregulation of cell adhesion molecules in leukemia

R Windisch, N Pirschtat, C Kellner, L Chen-Wichmann… - Cancers, 2019 - mdpi.com
… of the mechanisms by which leukemogenic gene products hijack control of cellular
adhesion to subsequently disturb normal hematopoiesis and promote leukemia development. …

The hematopoietic system

BD Car, DM Seelig - Schalm's veterinary hematology, 2022 - Wiley Online Library
hematopoiesis and that there may be other homeostatic mechanisms that control hematopoiesis
of a few surface adhesion receptors, such a CD36 (thrombospondin receptor) and VLA-4…