Dynamic role of LMW-hyaluronan fragments and Toll-like receptors 2, 4 in progression of bleomycin induced lung parenchymal injury to fibrosis
A Pandey, R Kulshrestha, SK Bansal - The Egyptian Journal of …, 2021 - Springer
… Pulmonary fibrosis is a progressive lung disease characterized by aberrant tissue repair,
excessive … Weak CD68 positive macrophages were seen in saline control lungs and on day 0 …
excessive … Weak CD68 positive macrophages were seen in saline control lungs and on day 0 …
Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice
… regulate AEC2 renewal are incompletely understood. We provide evidence that expression
of the innate immune receptor Toll-like receptor … renewal, repair of lung injury and limiting the …
of the innate immune receptor Toll-like receptor … renewal, repair of lung injury and limiting the …
Hyaluronan interactions with innate immunity in lung biology
RM Tighe, S Garantziotis - Matrix Biology, 2019 - Elsevier
… Hyaluronan-innate immune interactions in lung injury are … central role for hyaluronan in the
regulation of lung immunity, in … The prototypical PPRs are the Toll like receptors (TLR). At this …
regulation of lung immunity, in … The prototypical PPRs are the Toll like receptors (TLR). At this …
Damage-associated molecular patterns and their signaling pathways in primary blast lung injury: New research progress and future directions
N Li, C Geng, S Hou, H Fan, Y Gong - International journal of molecular …, 2020 - mdpi.com
… These interventions aim to control the development of the disease … Hyaluronic acid acts as
an important component of … -induced heat shock proteins with toll-like receptor-bearing cells of …
an important component of … -induced heat shock proteins with toll-like receptor-bearing cells of …
Lung Hyaluronasome: Involvement of Low Molecular Weight Ha (Lmw-Ha) in Innate Immunity
A Hoarau, M Polette, C Coraux - Biomolecules, 2022 - mdpi.com
… is regulated by the transmembrane enzymes hyaluronan … interactions with Toll-Like Receptors
(TLR2 and TLR4). TLR … LPS-induced lung inflammation and lung injury in ventilated rats […
(TLR2 and TLR4). TLR … LPS-induced lung inflammation and lung injury in ventilated rats […
Toll-like receptor agonists modulate wound regeneration in airway epithelial cells
A Lewandowska-Polak, M Brauncajs… - International journal of …, 2018 - mdpi.com
… , may induce injuries of airway epithelium, requiring a regulated repair mechanism to restore
the protective barrier [1,2]. A wound repair process starts quickly after injury and includes …
the protective barrier [1,2]. A wound repair process starts quickly after injury and includes …
Hyaluronan fragmentation during inflammatory pathologies: a signal that empowers tissue damage
A Avenoso, G Bruschetta, A D'Ascola… - Mini Reviews in …, 2020 - ingentaconnect.com
… lung disease. In this context, the covalent HC-HA binding, which is regulated by TSG-6, is
fundamental in the prime or the recovery of lung inflammation in acute lung damage caused by …
fundamental in the prime or the recovery of lung inflammation in acute lung damage caused by …
Hyaluronan and halogen‐induced airway hyperresponsiveness and lung injury
… HAS gene expression is regulated by a wide range of … most relevant in environmental lung
injury as described below; … via binding to its receptors, CD44 Toll-like receptor (TLR) 2, and …
injury as described below; … via binding to its receptors, CD44 Toll-like receptor (TLR) 2, and …
Proteoglycans in Toll-like receptor responses and innate immunity
S Garantziotis, RC Savani - American Journal of Physiology …, 2022 - journals.physiology.org
… in the regulation of the immune response to injury and strongly … outstanding reviews on
hyaluronan-immune interactions … been found in chronic obstructive pulmonary disease (COPD), …
hyaluronan-immune interactions … been found in chronic obstructive pulmonary disease (COPD), …
Hyaluronan and its interactions with immune cells in the healthy and inflamed lung
… The panel on the right is a control, showing a lung section from day 7 BLM, after treatment …
lung injury, and Escherichia coli (53), Klebsiella pneumoniae (54), or Influenza infection (55). …
lung injury, and Escherichia coli (53), Klebsiella pneumoniae (54), or Influenza infection (55). …