Hyaluronan fragments produced during tissue injury: A signal amplifying the inflammatory response
A Avenoso, G Bruschetta, A D'Ascola… - Archives of biochemistry …, 2019 - Elsevier
… play opposite functions in the regulation of inflammation. A study … a marked down-regulation
of the A2a receptor. CD44 was … HA fragments exert A2aR down-regulation in vivo model of …
of the A2a receptor. CD44 was … HA fragments exert A2aR down-regulation in vivo model of …
Connection between Hyaluronic Acid and Toll-Like Receptor in Signal Transduction
C Fan, H Wang - … Technology (CSET2015) & Medical Science and …, 2016 - World Scientific
… [19] also demonstrated that TLR-2 and TLR-4 were related with signal production in lung
injury. … Role of hyaluronic acid and toll-like receptor 4 in regulation of inflammatory liver injury. …
injury. … Role of hyaluronic acid and toll-like receptor 4 in regulation of inflammatory liver injury. …
Integration of canonical and noncanonical pathways in TLR4 signaling: complex regulation of the wound repair program
PJ McKeown-Longo, PJ Higgins - Advances in wound care, 2017 - liebertpub.com
… The toll-like receptor (TLR) system is a critical node in the … Gefitinib and erlotinib reduce
pulmonary damage and promote … Macrophage TGF-β induction by the DAMP ligand hyaluronan …
pulmonary damage and promote … Macrophage TGF-β induction by the DAMP ligand hyaluronan …
Low‐molecular‐mass hyaluronan induces pulmonary inflammation by up‐regulation of Mcl‐1 to inhibit neutrophil apoptosis via PI 3K/Akt1 pathway
H Zhao, Y Ma, L Zhang - Immunology, 2018 - Wiley Online Library
… Because the suppression of neutrophil apoptosis in acute lung injury is associated with the
… /Akt1-regulated pro-inflammatory responses additionally correlate with the Toll-like receptor (…
… /Akt1-regulated pro-inflammatory responses additionally correlate with the Toll-like receptor (…
[HTML][HTML] Targeting Toll-like receptors with soluble Toll-like receptor 2 prevents peritoneal dialysis solution–induced fibrosis
AC Raby, GT González-Mateo, A Williams, N Topley… - Kidney International, 2018 - Elsevier
… Hsp70 and hyaluronan (HA) induce Toll-like receptor (TLR)-mediated pro-inflammatory …
We tested the inflammation regulatory capacity of the inhibitor of TLRs, soluble Toll-like …
We tested the inflammation regulatory capacity of the inhibitor of TLRs, soluble Toll-like …
Damage Associated Molecular Patterns from the extracellular matrix in Chronic Obstructive Pulmonary Disease
D Piebenga - 2020 - fse.studenttheses.ub.rug.nl
… CD4+ T-cell and a decrease in regulatory T-cells in lung tissue. … Toll-Like Receptors (TLRs),
NOD-Like receptors (NLRs) and the … Its binding of hyaluronan in the ECM creates a aqueous …
NOD-Like receptors (NLRs) and the … Its binding of hyaluronan in the ECM creates a aqueous …
[HTML][HTML] Attenuation of radiation-induced lung injury by hyaluronic acid nanoparticles
A Lierova, J Kasparova, J Pejchal… - Frontiers in …, 2020 - frontiersin.org
… lung tissue. We examined the effects after gamma irradiation of hyaluronic acid nanoparticles
(HANPs) applied into lung … in a dose causing radiation-induced pulmonary injuries (RIPI). …
(HANPs) applied into lung … in a dose causing radiation-induced pulmonary injuries (RIPI). …
Multiwalled carbon nanotube functionalization with high molecular weight hyaluronan significantly reduces pulmonary injury
… Hyaluronan functionalization reduces lung injury potential of nanotubes. (A) BAL fluid cell
differentials in C57Bl/6J female mice (6–9 animals per group) at day 1 postexposure after …
differentials in C57Bl/6J female mice (6–9 animals per group) at day 1 postexposure after …
Knockdown of versican 1 in lung fibroblasts aggravates Lipopolysaccharide-induced acute inflammation through up-regulation of the SP1-Toll-like Receptor 2-NF-κB …
L Xu, W Hu, J Zhang, J Qu - International Immunopharmacology, 2023 - Elsevier
… later stages such as the abnormal repair stage and fibrosis. The role of V1 is somewhat
circumstantial and dependent of other interactive components like hyaluronan, implying that the …
circumstantial and dependent of other interactive components like hyaluronan, implying that the …
Toll‐like receptors and tissue remodeling: the pro/cons recent findings
… The discovery of Toll-like receptors (TLRs) and their smart functions that bridge innate and
… well documented, TLR regulation is largely unexplored. These regulatory mechanisms might …
… well documented, TLR regulation is largely unexplored. These regulatory mechanisms might …