CD4+ follicular regulatory T cells optimize the influenza virus–specific B cell response

Y Lu, R Jiang, AW Freyn, J Wang… - Journal of Experimental …, 2020 - rupress.org
… We reason that in live viral infection, such as with influenza virus, a complex antigen with
distinct epitopes and antigen persistence due to replication, the maintenance of diverse B …

The dual role of regulatory T cells in hepatitis B virus infection and related hepatocellular carcinoma

J He, R Miao, Y Chen, H Wang, M Liu - Immunology, 2024 - Wiley Online Library
… CD4 + T lymphocytes that … regulatory T cells (nTregs) and induced regulatory T cells (iTregs)
[11]. While nTregs arise in the thymus, iTregs are derived from naive CD4 + T lymphocytes

[HTML][HTML] The pivotal role of regulatory T cells in the regulation of innate immune cells

EB Okeke, JE Uzonna - Frontiers in immunology, 2019 - frontiersin.org
… + T cells with regulatory phenotype (regulatory T cells; Tregs), which constitute a part of the
adaptive immune system, have been widely implicated in the regulation of … in viral infections. …

[HTML][HTML] Manipulation of regulatory cells' responses to treatments for chronic hepatitis B virus infection

S Tavakolpour, SM Alavian, S Sali - Hepatitis Monthly, 2016 - ncbi.nlm.nih.gov
… levels of regulatory cytokines and also regulatory T cells (Tregs) … cells are deeply involved
in CHB infection. The inhibition of regulatory T cells may reverse the dysfunction of effector T

Role of γδ T cells in controlling viral infections with a focus on influenza virus: implications for designing novel therapeutic approaches

A Sabbaghi, SM Miri, M Keshavarz, M Mahooti… - Virology journal, 2020 - Springer
… of γδ T cells in defense to influenza virus infection and how … protective immune responses
against infected cells. The results … of CD4 + T cells, CD8 + T cells, and regulatory T cells (Tregs)…

Role of regulatory T cells and inhibitory molecules in the development of immune exhaustion during human immunodeficiency virus type 1 infection

SM Gonzalez, W Zapata, MT Rugeles - Viral immunology, 2016 - liebertpub.com
… response of regulatory T cells and recently also to the expression in different cell populations
of … role during chronic viral infections; this phenomenon has been described during chronic …

Regulatory T cells suppress virus-specific antibody responses to Friend retrovirus infection

TC Moore, RJ Messer, KJ Hasenkrug - PLoS One, 2018 - journals.plos.org
… that regulatory T cells (Tregs) constrain the magnitude of B cell … in live influenza infections
where Tregs promoted B cell and … B cell responses, especially during live viral infections. Here, …

Interleukin-21 modulates balance between regulatory T cells and T-helper 17 cells in chronic hepatitis B virus infection

Y Cai, H Ji, X Zhou, K Zhao, X Zhang, L Pan… - BMC Infectious …, 2023 - Springer
… Chronic HBV infection is always accompanied by differences in the balance between regulatory
T cells (Tregs) and T-helper 17 (Th17) cells in infection phases. IL-21 plays an important …

Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology

CJ Pyle, FI Uwadiae, DP Swieboda, JA Harker - PLoS pathogens, 2017 - journals.plos.org
… we used murine models of respiratory virus infection. RSV infection resulted in increased IL-6
… Overall we found that during respiratory virus infection the prototypic inflammatory cytokine …

Role of CD4+ T cells in the control of viral infections: recent advances and open questions

J Kervevan, LA Chakrabarti - International Journal of Molecular Sciences, 2021 - mdpi.com
… Persisting immunoregulatory conditions such as TCR stimulation in an environment rich
in IL-10 and IL-27 lead to the induction of specialized CD4+ regulatory T cells called Tr1 [64]. …