Fish embryo tests and acute fish toxicity tests are interchangeable in the application of the threshold approach
JM Rawlings, SE Belanger… - Environmental …, 2019 - Wiley Online Library
… animal use and satisfying international regulatory needs and requirements. The threshold …
, 82 were used in threshold approach comparisons with Daphnia and algal acute toxicity data. …
, 82 were used in threshold approach comparisons with Daphnia and algal acute toxicity data. …
Limitations of animal studies for predicting toxicity in clinical trials: is it time to rethink our current approach?
GA Van Norman - JACC: Basic to Translational Science, 2019 - jacc.org
… toxicity tests for which both animal and human data are available. In a review of 2,366 drugs,
including data … Increasingly, scientific organizations and government regulatory agencies …
including data … Increasingly, scientific organizations and government regulatory agencies …
Patient-reported outcomes in the evaluation of toxicity of anticancer treatments
… practice, and for regulatory authorities. Systematic collection … as part of routine toxicity data
collection and reporting of … the patient perspective on toxicity reporting into widespread use in …
collection and reporting of … the patient perspective on toxicity reporting into widespread use in …
Per‐and polyfluoroalkyl substances (PFAS) in surface water near US Air Force bases: Prioritizing individual chemicals and mixtures for toxicity testing and risk …
A East, RH Anderson, CJ Salice - … Toxicology and Chemistry, 2021 - Wiley Online Library
… results can be used to provide perspective on toxicity testing, … led to various management
and regulatory actions. One PFAS … other field data on PFAS and available toxicity data, provide …
and regulatory actions. One PFAS … other field data on PFAS and available toxicity data, provide …
Suspect screening and regulatory databases: a powerful combination to identify emerging micropollutants
P Gago-Ferrero, A Krettek, S Fischer… - … science & technology, 2018 - ACS Publications
… toxicity data in the prioritization approach since … toxicity were also detected (eg, stearic acid
or tetraethylene glycol). In future prioritization strategies, it would be useful to include toxicity …
or tetraethylene glycol). In future prioritization strategies, it would be useful to include toxicity …
Exploring current read-across applications and needs among selected US Federal Agencies
G Patlewicz, LE Lizarraga, D Rua, DG Allen… - Regulatory Toxicology …, 2019 - Elsevier
… approach could conceivably be the most practical and pragmatic solution for acute fish toxicity,
a defined approach 2 making use of … However, DoD generates and uses toxicity data with …
a defined approach 2 making use of … However, DoD generates and uses toxicity data with …
[HTML][HTML] Current EU research activities on combined exposure to multiple chemicals
SK Bopp, R Barouki, W Brack, S Dalla Costa… - Environment …, 2018 - Elsevier
… From the recommendations of this report, EFSA initiated data collection on mixture toxicity for
human … This approach will be gradually introduced in regulating the use of pesticides in the …
human … This approach will be gradually introduced in regulating the use of pesticides in the …
Quantitative Read-across structure-activity relationship (q-RASAR): A new approach methodology to model aquatic toxicity of organic pesticides against different fish …
S Ghosh, M Chatterjee, K Roy - Aquatic Toxicology, 2023 - Elsevier
… Regulatory agencies such as the European Chemicals Agency (… fish) toxicity data prediction
of the PPDB pesticides, this study will be an effective alternative approach for aquatic toxicity …
of the PPDB pesticides, this study will be an effective alternative approach for aquatic toxicity …
Advances of the QSAR approach as an alternative strategy in the environmental risk assessment
LM Saavedra, JCG Martinez, PR Duchowicz - QSAR in safety evaluation …, 2024 - Elsevier
… Nowadays, several regulatory entities have gradually demanded acute and chronic toxicity
data from proper and well-established toxicity assays as part of their procedures to register …
data from proper and well-established toxicity assays as part of their procedures to register …
Toward global and national toxicity footprints
… an integrative approach to evaluate the global toxicity footprint by … in national regulations,
crops, type of active ingredients used and … The data used to create this figure can be found in …
crops, type of active ingredients used and … The data used to create this figure can be found in …