Fish embryo tests and acute fish toxicity tests are interchangeable in the application of the threshold approach

JM Rawlings, SE Belanger… - Environmental …, 2019 - Wiley Online Library
… animal use and satisfying international regulatory needs and requirements. The threshold …
, 82 were used in threshold approach comparisons with Daphnia and algal acute toxicity data. …

Limitations of animal studies for predicting toxicity in clinical trials: is it time to rethink our current approach?

GA Van Norman - JACC: Basic to Translational Science, 2019 - jacc.org
toxicity tests for which both animal and human data are available. In a review of 2,366 drugs,
including data … Increasingly, scientific organizations and government regulatory agencies …

Patient-reported outcomes in the evaluation of toxicity of anticancer treatments

M Di Maio, E Basch, J Bryce, F Perrone - Nature reviews Clinical …, 2016 - nature.com
… practice, and for regulatory authorities. Systematic collection … as part of routine toxicity data
collection and reporting of … the patient perspective on toxicity reporting into widespread use in …

Per‐and polyfluoroalkyl substances (PFAS) in surface water near US Air Force bases: Prioritizing individual chemicals and mixtures for toxicity testing and risk …

A East, RH Anderson, CJ Salice - … Toxicology and Chemistry, 2021 - Wiley Online Library
… results can be used to provide perspective on toxicity testing, … led to various management
and regulatory actions. One PFAS … other field data on PFAS and available toxicity data, provide …

Suspect screening and regulatory databases: a powerful combination to identify emerging micropollutants

P Gago-Ferrero, A Krettek, S Fischer… - … science & technology, 2018 - ACS Publications
toxicity data in the prioritization approach since … toxicity were also detected (eg, stearic acid
or tetraethylene glycol). In future prioritization strategies, it would be useful to include toxicity

Exploring current read-across applications and needs among selected US Federal Agencies

G Patlewicz, LE Lizarraga, D Rua, DG Allen… - Regulatory Toxicology …, 2019 - Elsevier
approach could conceivably be the most practical and pragmatic solution for acute fish toxicity,
a defined approach 2 making use of … However, DoD generates and uses toxicity data with …

[HTML][HTML] Current EU research activities on combined exposure to multiple chemicals

SK Bopp, R Barouki, W Brack, S Dalla Costa… - Environment …, 2018 - Elsevier
… From the recommendations of this report, EFSA initiated data collection on mixture toxicity for
human … This approach will be gradually introduced in regulating the use of pesticides in the …

Quantitative Read-across structure-activity relationship (q-RASAR): A new approach methodology to model aquatic toxicity of organic pesticides against different fish …

S Ghosh, M Chatterjee, K Roy - Aquatic Toxicology, 2023 - Elsevier
Regulatory agencies such as the European Chemicals Agency (… fish) toxicity data prediction
of the PPDB pesticides, this study will be an effective alternative approach for aquatic toxicity

Advances of the QSAR approach as an alternative strategy in the environmental risk assessment

LM Saavedra, JCG Martinez, PR Duchowicz - QSAR in safety evaluation …, 2024 - Elsevier
… Nowadays, several regulatory entities have gradually demanded acute and chronic toxicity
data from proper and well-established toxicity assays as part of their procedures to register …

Toward global and national toxicity footprints

A Leclerc, E Berthet, K Stadler, R Wood… - Journal of Industrial …, 2023 - Wiley Online Library
… an integrative approach to evaluate the global toxicity footprint by … in national regulations,
crops, type of active ingredients used and … The data used to create this figure can be found in …