… describes the activities and regulatory modes of TCF/LEF as transcriptional repressors, with
… of TCF7L1 repressor activities in both SO formation, and forebrain progenitor proliferation. …

… acts in anterior development and is critical for eye formation. … In non-vertebrates transcriptional
activation and repression is … /Tle co-repressor proteins make a crucial contribution to eye …

… To assess if tcf7l2 repressor activity can functionally compensate for loss of tcf7l1a, we …
Repressor activity of headless/Tcf3 is essential for vertebrate head formation. Nature 407:…

… The repressor activity of Tcf7l1 has been shown to be crucial … is also essential for the formation
of the vertebrate eye. In … in the lens surface ectoderm is a key prerequisite for lens placode …

… formation 38,39 , suggesting that they could be responsible for the observed Rspo2 activity.
… is predicted to be rescued by a constitutive TCF3 repressor that does not bind β-catenin (∆…

… repressors to potential Wnt targets in the Xenopus gastrula. … The repressive activity of TCF3
is essential for its role in dorsal… , a gap in expression is formed in ring genes, whereas if we …

… Abstract The vertebrate eye originates from the eye field, a domain of cells specified by a …
due to TRiC/TCP-1 chaperone activity or an independent function of Cct5 we knocked down …

… repressor of maternal β-catenin signaling to safeguard the embryo against hyperactivation of
maternal β-catenin activity … -catenin activity is crucial for proper dorsoventral axis formation. …

… Using mouse genetics, we show that TCF7L1 acts as a transcriptional repressor to regulate
… repressor activity of TCF7L1 is required for normal HP axis formation in mice and humans. …

… ) is crucial for the evolutionary diversification of vertebrates. … /β-catenin repressor, is
required to maintain anterior neural … This suggests that Tcf7l1, by forming a boundary to the …