Repurposing some older drugs that cross the blood–brain barrier and have potential anticancer activity to provide new treatment options for glioblastoma

D Rundle‐Thiele, R Head, L Cosgrove… - British journal of …, 2016 - Wiley Online Library
D Rundle‐Thiele, R Head, L Cosgrove, JH Martin
British journal of clinical pharmacology, 2016Wiley Online Library
Glioblastoma is a brain neoplasm with limited 5‐year survival rates. Developments of new
treatment regimens that improve patient survival in patients with glioblastoma are needed. It
is likely that a number of existing drugs used in other conditions have potential anticancer
effects that offer significant survival benefit to glioblastoma patients. Identification of such
drugs could provide a novel treatment paradigm.
Glioblastoma is a brain neoplasm with limited 5‐year survival rates. Developments of new treatment regimens that improve patient survival in patients with glioblastoma are needed. It is likely that a number of existing drugs used in other conditions have potential anticancer effects that offer significant survival benefit to glioblastoma patients. Identification of such drugs could provide a novel treatment paradigm.
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