… Interestingly, we found that only CD4 + T cells were the only cell type examined that delayed
host … Nonetheless, because we show that either CD4 + or CD8 + T cells are required, C. …

… These data conclusively show that Th1-polarized CD4 + T cells are required to directly or
indirectly orchestrate a catastrophic inflammatory cascade that can lead to the CNS damage …

… required CD4 T cells [58,61]. However, the loss of CD4 T cells resulted in a hyperexpansion
of CD8 T cells [59]. … using human cells showed that (a) proliferation of CD8 T cells requires …

… in host adaptive immunity [CD4 + T cells, CD8 + T cells, … the Th1 response and develop host
resistance against C. … disease, and more than one type of vaccine may be required. Over the …

… Cryptococcus neoformans classically targets … advanced HIV-AIDS, various T cell deficiencies,
pregnancy, chronic … is a major requirement for fungal persistence in the mammalian host, …

… No phospho-STAT3-positive cells were detected in CD8 + or γδ T cell subsets. Previous …
findings that phospho-STAT1 in T cells is not associated with C. neoformans stimulation (48, 49)…

… of TCRβ+ T cells and CD4+ T cells were quantified after … neoformans–infected lungs, we
also show that it is required for the … regulator of T cell responses that is required for pulmonary …

… Then we found the cutoff value of CD4 + T cell counts of 400/uL for predicting dissemination;
the sensitivity and specificity were 80% and 98.2%. The area under concentration-time …

… FIG 1 The time required for the host to completely eradicate chitosan-deficient cda1Δ2Δ3Δ
… increased recruitment of Th1-type CD4 + T cells is able to trigger protective immunity, we first …

… that either CD4 + or CD8 + T cells are required for C. neoformans Δsgl1-mediated host … of
HK vaccination and promote stronger adaptive T cell-mediated immunity as seen with other HK …