Cryptococcus neoformans Infection Induces IL-17 Production by Promoting STAT3 Phosphorylation in CD4+ T Cells
X Guo, X Mao, D Tian, Y Liao, B Su, C Ye… - Frontiers in …, 2022 - frontiersin.org
… No phospho-STAT3-positive cells were detected in CD8 + or γδ T cell subsets. Previous …
findings that phospho-STAT1 in T cells is not associated with C. neoformans stimulation (48, 49)…
findings that phospho-STAT1 in T cells is not associated with C. neoformans stimulation (48, 49)…
Immunology of cryptococcal infections: developing a rational approach to patient therapy
W Elsegeiny, KA Marr, PR Williamson - Frontiers in immunology, 2018 - frontiersin.org
… Immunophenotyping and dendritic cell-T cell signaling … by either Cryptococcus neoformans
and Cryptococcus gattii. … the T-cell/monocyte signaling pathway that is required for a …
and Cryptococcus gattii. … the T-cell/monocyte signaling pathway that is required for a …
The CD4+ T-lymphocyte count is an important predictor for the prognosis of cryptococcosis
Y Ding, P Li, Q He, H Wei, T Wu, D Xia, M Tan… - European Journal of …, 2017 - Springer
… Then we found the cutoff value of CD4 + T cell counts of 400/uL for predicting dissemination;
the sensitivity and specificity were 80% and 98.2%. The area under concentration-time …
the sensitivity and specificity were 80% and 98.2%. The area under concentration-time …
[HTML][HTML] Vaccine protection by Cryptococcus neoformans Δsgl1 is mediated by γδ T cells via TLR2 signaling
TG Normile, TH Chu, BS Sheridan, M Del Poeta - Mucosal immunology, 2022 - Elsevier
… complete host protection in condition of CD4 + T cell deficiency. … T cells in the lungs were
significantly increased in C. … whether γδ T cells were required for host protection using TCRδ −…
significantly increased in C. … whether γδ T cells were required for host protection using TCRδ −…
A holistic review on Cryptococcus neoformans
SS Rathore, J Sathiyamoorthy, C Lalitha… - Microbial …, 2022 - Elsevier
… immunity by maturation of CD4 and CD8 T cells (recruiting macrophage to the lungs in
pulmonary infection). T-cells derived Th1 and Th2 type cytokines assist to manage pathogens. …
pulmonary infection). T-cells derived Th1 and Th2 type cytokines assist to manage pathogens. …
Cryptococcus neoformans Infection in the Central Nervous System: The Battle between Host and Pathogen
Y Chen, ZW Shi, AB Strickland, M Shi - Journal of Fungi, 2022 - mdpi.com
… are impaired [1,140], demonstrating the essential role of T cells in host defense against C. …
that both CD4 + and CD8 + T cells are required to clear C. neoformans infection [141,142,143,…
that both CD4 + and CD8 + T cells are required to clear C. neoformans infection [141,142,143,…
Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses
… immune response needs to be at a certain concentration to elicit the response. … activation,
normal T cell expressed and secreted (RANTES), and tumor necrosis factor alpha (TNF-α). …
normal T cell expressed and secreted (RANTES), and tumor necrosis factor alpha (TNF-α). …
Identification of pathogen genomic differences that impact human immune response and disease during Cryptococcus neoformans infection
… associated with melanin production (which is not required for killing of C. elegans); thus, the
… participant mortality due to cryptococcosis (days after initial diagnosis), CD4 + T-cell count, …
… participant mortality due to cryptococcosis (days after initial diagnosis), CD4 + T-cell count, …
Immunological correlates of protection mediated by a whole organism Cryptococcus neoformans vaccine deficient in chitosan
C Specht, R Wang, LVN Oliveira, MM Hester… - bioRxiv, 2024 - biorxiv.org
… of B cells, CD8+ T cells, and CD4+ T cells to 106 protection against cryptococcosis mediated
by … However, our data demonstrate that CD8+ T cells were not required for protection 257 …
by … However, our data demonstrate that CD8+ T cells were not required for protection 257 …
Naïve B cells reduce fungal dissemination in Cryptococcus neoformans infected Rag1−/− mice
… in CD4 cell-reconstituted Rag1 −/− than mice that did not receive CD4 cells,Citation 18 but
the effect of B cells … with a previous study in which B cells were required to protect against C. …
the effect of B cells … with a previous study in which B cells were required to protect against C. …