Resveratrol reduces liver endoplasmic reticulum stress and improves insulin sensitivity in vivo and in vitro

H Zhao, Y Zhang, L Shu, G Song… - Drug design, development …, 2019 - Taylor & Francis
resveratrol failed to reduce body weight and insulin levels of HFD fed mice, it lowered blood
glucose levels, and increased the QUICKI index (used to assess insulin resistance), … Akt or …

[PDF][PDF] … of insulin sensitivity and maintenance of glucose homeostasis in insulin-sensitive tissues via PPAR-γ and through activation of PI3K/p-Akt signaling pathway by …

F Mohammed, A Gurigis, W Abdel-Mageed… - J Mol Immunol, 2018 - researchgate.net
… suggests that there is a close link between hyperglycemia, oxidative stress, and diabetic
complications. Resveratrol a polyphenolic compound found in various natural food products. …

The role of resveratrol in diabetes and obesity associated with insulin resistance

M Hoca, E Becer, HS Vatansever - Archives of physiology and …, 2023 - Taylor & Francis
… ) mice), resveratrol was reported to reduce oxidative stress and improve pancreatic islet
structure … kinase B (Akt)-signalling pathway was activated by resveratrol and enhanced glucose …

Role of resveratrol in the management of insulin resistance and related conditions: Mechanism of action

E Abbasi Oshaghi, MT Goodarzi… - Critical reviews in …, 2017 - Taylor & Francis
… of RES, the mechanisms leading to improved insulin sensitivity, and its clinical role in the …
decrease in oxidative stress and a significant increase in AKT phosphorylation ( Figure 5 ). …

Resveratrol ameliorates metabolic disorders and insulin resistance in high-fat diet-fed mice

L Gong, S Guo, Z Zou - Life sciences, 2020 - Elsevier
… Antioxidant drugs, vitamins E and N-acetyl-cysteine, ameliorate metabolic disorders and
insulin resistance by reducing oxidative stress [40,41]. RSV, a natural antioxidant, eliminates …

… -induced mouse benign prostatic hyperplasia (BPH) is improved by treatment with resveratrol: implication of oxidative stress, insulin sensitivity and neuronal growth …

FB Calmasini, MG de Oliveira, EC Alexandre… - The Journal of …, 2018 - Elsevier
resveratrol could ameliorate the obesity-induced mouse BPH by improving the oxidative
status and insulin sensitivity. … prostatic insulin sensitivity focusing on AKT phosphorylation. The …

[HTML][HTML] Disease-associated regulation of gene expression by resveratrol: Special focus on the PI3K/AKT signaling pathway

S Ghafouri-Fard, Z Bahroudi, H Shoorei… - Cancer Cell …, 2022 - Springer
… that reported modulatory effects of resveratrol on PI3K/AKT signaling pathway. … , resveratrol
via the PI3K/AKT-mediated Nrf2 pathway could protect intestinal cells against oxidative stress

[HTML][HTML] Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: Systematic review and meta-analysis

X Zhu, C Wu, S Qiu, X Yuan, L Li - Nutrition & metabolism, 2017 - Springer
… of resveratrol on glycemic control and insulin sensitivity among … of resveratrol treatment
improved insulin resistance and … that activating inflammatory pathways and oxidative stress

Resveratrol improves glucose uptake in insulin-resistant adipocytes via Sirt1

S Chen, Z Zhao, L Ke, Z Li, W Li, Z Zhang… - The Journal of nutritional …, 2018 - Elsevier
… In this study, we have demonstrated that Res can improve insulin sensitivity in insulin-resistant
adipocytes by Sirt1-p-AMPK-p-AKT and Sirt1-p-IRS-1-p-AKT pathway, thus promoting …

Resveratrol bidirectionally regulates insulin effects in skeletal muscle through alternation of intracellular redox homeostasis

Y Quan, S Hua, W Li, M Zhan, Y Li, L Lu - Life sciences, 2020 - Elsevier
decreased activation of the insulin-induced AKT signaling. In skeletal muscle of insulin
resistance, RV reduced oxidative stress… ) level, and enhanced insulin-induced AKT activation and …