… by excess, yet reversible, fat accumulation in the … insulin action, the fat-induced liver insulin
resistance causes a slight rise in fasting plasma glucose and triggers an increase in insulin …

… is reversible, emphasizing the importance of … roles of specific plasma lipid or fatty acid
species in promoting or preventing CVD and the importance of therapeutically modifying plasma …

… diet induced insulin resistance and obesity on lipid profile in … diabetes may lead to the
pronounced salivary glands lipids … easily reversible after barely 1 week of insulin administration. …

… reversible condition, but if untreated leads to type 2 diabetes alongside increasing
cardiovascular risk. The link between obesity … of the lipid remodeling occurring in insulin-sensitive …

… factors proposed to induce insulin resistance, including … insulin resistance that links these
mediators to final common pathways of metabolite-driven gluconeogenesis and ectopic lipid …

… Acromegaly constitutes a unique human in vivo model to study reversible insulin resistance
… of insulin resistance dissociated from obesity. We studied twenty-one patients with newly …

… mechanisms of improved insulin sensitivity in skeletal muscle… insulin sensitivity without
improving mitochondrial function (… (17) in obese people; however, whether these declines in lipid …

… 2 diabetes that clusters in families must be considered. The condition does not occur unless
β-cell function is no longer sufficient to overcome insulin resistance (16)… to lipid availability is …

… to impaired pancreatic beta cell function that results in the development of type 2 diabetes. …
that type 2 diabetes is reversible in patients who undergo bariatric surgery for obesity 11 - 13 …

… In conclusion, the lipid- induced insulin resistance or lipotoxicity hypothesis proposes that
in … The observation of rapid reversibility of hepatic but not muscle insulin resistance with …