… Alzheimer’s disease (AD) is a neurodegenerative disorder … cholinergic nerve terminals was
evident in 4-month-old homozygous PDAPP mice, no difference in the number of cholinergic …

… the Alzheimer’s disease brain may be reflecting, at least in part, a loss of function phenotype
in memory processing. Here we take BACE1 translation … Its translation is governed by eIF2α …

… Alzheimer’s disease (AD) represents the most frequent type of dementia in elderly people.
Two major forms of the disease exist: sporadic - the causes of which have not yet been fully …

… changes while drugs that boosting cholinergic system (eg, by AChE … cholinergic hypothesis
has been implicated in the AD etiology and it is based on the degeneration of cholinergic …

… proposes a new hypothesis for Alzheimer’s disease (… cholinergic hypothesis, which emerged
in the 1980s, sought to explain the disease in terms of reduced synthesis of acetylcholine …

… The development and successful clinical translation of 18FFEOBV was a breakthrough for …
revisited: anatomy, history and differential involvement in Alzheimer’s and Parkinson’s disease…

… translation of findings. This article analyzes the discrepancies between animal models and
human AD pathology that complicate the translation of … to propose a new perspective on this …

… Emerging evidence highlights a critical role for microglia in … of Alzheimer's Disease, the
cholinergic hypothesis remains both a … in understanding AD, the translation of this knowledge into …

… This includes looking back, reactivating, and revisiting findings … data, the translation of the
amyloid cascade hypothesis into … In the early 1980s, the “Cholinergic Hypothesis of AD” was …

… anticholinergics, within a framework of the cholinergic hypothesis of AD and AD-associated …
of trophic factor hypothesis of AD”, we propose that AChE inhibitors enhance acetylcholine-…