Regulation of oxidized LDL-induced proliferation and migration in human vascular smooth muscle cells by a novel circ_0007478/miR-638/ROCK2 ceRNA network

Z Guan, R Lu, Y Sun, X Wang, C Yu… - Vascular …, 2023 - journals.sagepub.com
… smooth muscle cells (VSMCs) under oxidized low-density … )-638, and rho-associated
protein kinase 2 (ROCK2) levels … -638 is tightly linked to vulnerable atherosclerotic plaques in …

ROCK inhibition may stop diabetic kidney disease

K Matoba, Y Takeda, Y Nagai, Y Kanazawa… - JMA journal, 2020 - jstage.jst.go.jp
Rho-associated coiled-coilcontaining kinase 2 deficiency in bone marrow-derived cells
leads to increased cholesterol efflux and decreased atherosclerosis. Circulation. 2012;126(18):…

[PDF][PDF] Role of Inflammation in Development of Atherosclerosis

K Szilagyi - 2016 - research.vu.nl
… In fact, hypercholesterolemia with defective cholesterol effluxRho-associated coiled-coil-containing
kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol

Endothelial Function in dyslipidemia: roles of LDL-cholesterol, HDL-cholesterol and triglycerides

Y Higashi - Cells, 2023 - mdpi.com
… Endothelial dysfunction is the initial step for atherosclerosis … an increase in Rho-associated
kinase activity and a decrease … oxidation, decrease in oxidative stress, cholesterol efflux from …

A systematic review on rho-kinase as a potential therapeutic target for the treatment of erectile dysfunction

KA Zewdie, MA Ayza, BA Tesfaye… - … and Reports in …, 2020 - Taylor & Francis
… (ICP/MAP) was decreased due to age and various chronic … Rho-associated coil-forming
protein kinase (ROCK) is … , atherosclerosis, and pelvic irradiation) and medication side effects …

[HTML][HTML] Receptor for advanced glycation end products (RAGE) and mechanisms and therapeutic opportunities in diabetes and cardiovascular disease: insights from …

L Egaña-Gorroño, R López-Díez, G Yepuri… - Frontiers in …, 2020 - frontiersin.org
… ; Rho-associated, coiled-coil-containing protein kinase (… cholesterol efflux, significant
attenuation of vascular inflammation was observed upon deletion of Ager in diabetic atherosclerotic

Mechanistic and Therapeutic Insights of Macrophage MicroRNA in Atherosclerosis

MA Nguyen - 2019 - ruor.uottawa.ca
… development via modulating cholesterol efflux and inflammatory responses, thus … Bone-marrow
derived macrophages BSA … Rho-associated coiled-coil containing protein kinase 2 RVG …

[HTML][HTML] Monocyte-endothelial cell interactions in vascular and tissue remodeling

M Medrano-Bosch, B Simón-Codina… - Frontiers in …, 2023 - frontiersin.org
… activating RHO-associated coiled-coil containing protein kinase … and differentiation of bone
marrow-derived cells (BMCs). … target and treat macrophages in experimental atherosclerosis. …

Rho/Rho Kinase Signaling Pathway and Disease: from Bed to Bench

Y Wang, Y Zhang, D Zhang - Frontiers in Cardiovascular Drug …, 2022 - books.google.com
… Among them, Rho kinase, also known as Rho associated … Moreover, bone marrowderived
cells of Rock2 deletion or … also protects from atherosclerosis and reduces lipid deposition in …

Attenuation of obesity-induced insulin resistance in mice with heterozygous deletion of ROCK2

H Soliman, JN Varela, V Nyamandi… - International journal of …, 2016 - nature.com
Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells
leads to increased cholesterol efflux and decreased atherosclerosis. Circulation 2012; 126: 2236…