A systematic review on rho-kinase as a potential therapeutic target for the treatment of erectile dysfunction
KA Zewdie, MA Ayza, BA Tesfaye… - … and Reports in …, 2020 - Taylor & Francis
… (ICP/MAP) was decreased due to age and various chronic … Rho-associated coil-forming
protein kinase (ROCK) is … , atherosclerosis, and pelvic irradiation) and medication side effects …
protein kinase (ROCK) is … , atherosclerosis, and pelvic irradiation) and medication side effects …
Cardiac aging: from basic research to therapeutics
M Yan, S Sun, K Xu, X Huang, L Dou… - … and cellular …, 2021 - Wiley Online Library
… The deletion of Rho-associated coiled-coil-containing protein kinase (ROCK)1 … atherosclerosis
[95, 96]. mTOR inhibition triggers autophagy, promotes cell survival and cholesterol efflux, …
[95, 96]. mTOR inhibition triggers autophagy, promotes cell survival and cholesterol efflux, …
Attenuation of obesity-induced insulin resistance in mice with heterozygous deletion of ROCK2
H Soliman, JN Varela, V Nyamandi… - International journal of …, 2016 - nature.com
… Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells
leads to increased cholesterol efflux and decreased atherosclerosis. Circulation 2012; 126: 2236…
leads to increased cholesterol efflux and decreased atherosclerosis. Circulation 2012; 126: 2236…
[HTML][HTML] Data on gene and protein expression changes induced by apabetalone (RVX-208) in ex vivo treated human whole blood and primary hepatocytes
S Wasiak, D Gilham, LM Tsujikawa, C Halliday… - Data in brief, 2016 - Elsevier
… published in Atherosclerosis “RVX-208, a BET-inhibitor for Treating … T-cells; VSMC:
vascular smooth muscle cells; Italics indicates literature support for both pro-and anti-atherosclerotic …
vascular smooth muscle cells; Italics indicates literature support for both pro-and anti-atherosclerotic …
Discovery of novel highly selective Rho kinase (ROCK) inhibitory peptides and evaluation of their biological activities
R Abbasgholizadeh - 2017 - uh-ir.tdl.org
… Rho-associated kinases (ROCKs), a member of the AGC … to atherosclerosis pathogenesis.
Deletion of ROCK1 or ROCK2 in bone marrow–derived cells decreased inflammatory cells (…
Deletion of ROCK1 or ROCK2 in bone marrow–derived cells decreased inflammatory cells (…
Programmed cell death and lipid metabolism of macrophages in NAFLD
Z Xiao, M Liu, F Yang, G Liu, J Liu, W Zhao… - Frontiers in …, 2023 - frontiersin.org
… that aging led to increased necroptosis in liver macrophages and … via Rho-associated
coiled-coil-containing protein kinase (… An atherosclerosis-based study found that MLKL deficiency …
coiled-coil-containing protein kinase (… An atherosclerosis-based study found that MLKL deficiency …
Milk's role as an epigenetic regulator in health and disease
BC Melnik, G Schmitz - Diseases, 2017 - mdpi.com
… CPT1A, thus attenuates cholesterol efflux, hepatic LDL uptake, … Rho-associated coiled-coil
containing protein kinase 1 (… differentiation of human bone marrow-derived stem cells [267]. …
containing protein kinase 1 (… differentiation of human bone marrow-derived stem cells [267]. …
Efferocytosis in dendritic cells: an overlooked immunoregulatory process
Y Ma, T Jiang, X Zhu, Y Xu, K Wan, T Zhang… - Frontiers in …, 2024 - frontiersin.org
… kinase activity of the Rho-associated coiled-coil-containing … , which promotes cholesterol
efflux within the cell, plays a … /Rac1 signaling and reduces atherosclerotic lesion necrosis. J …
efflux within the cell, plays a … /Rac1 signaling and reduces atherosclerotic lesion necrosis. J …
Correlation of age of onset and clinical severity in Niemann–Pick disease type C1 with lysosomal abnormalities and gene expression
LL Baxter, DE Watkins-Chow, NL Johnson, NY Farhat… - Scientific reports, 2022 - nature.com
… , which are frequently identified due to increased clumsiness and learning … cell lines into
two groups (Fig. 4, Branches A and B) and genes into two groups with relatively high or low …
two groups (Fig. 4, Branches A and B) and genes into two groups with relatively high or low …
[PDF][PDF] COMBATING DIABETES AND DIABETIC KIDNEY DISEASE
SP Srivastava, J Goodwin, K Kanasaki - researchgate.net
… First, we discuss new leads targeted to DKD. In recent years … endothelial cells and its
deficiency influences cellular trans-… that LPS decreased the expression of LC3II and beclin-1, but …
deficiency influences cellular trans-… that LPS decreased the expression of LC3II and beclin-1, but …