… recent advance in Th17 memory formation and function in the chronic course of dry eye disease,
a major … Th17-mediated autoimmunity in dry eye pathogenesis. (1) Induction of adaptive …

… to ocular surface disease pathogenesis in a murine model of … in dry eye and that GM-CSF
promotes CD11b + cell … the role of Th17 cell-derived GM-CSF in the pathogenesis of …

… IL-17A secreted by Th17 cells finally infiltrates the … roles in the pathogenesis of DED. IL-6
and IL-23 are the inducing factors of Th17 cells, while IL-17A is the effect factor of Th17 cells. …

… cells that function primarily in antimicrobial defense but may participate in the dry eye
pathogenesis.… -17, produced by Th1 and Th17 cells, respectively, as critical effector cytokines in …

… roles of IL-7 and IL-15 signaling for the maintenance of memory Th17 cells, 10 we hypothesized
that IL-23 drives Th17 cells … on diminishing DED pathogenesis by rechallenging DED …

… Th17 cells and Tregs perform completely different functions in the pathogenesis of inflammatory
… the balance between Th17 and Treg is very important not only in the pathogenesis of the …

… of the tear film accompanied by ocular symptoms in which tear film instability and … and
neurosensory abnormalities play etiological roles”. Citation4 Although the pathogenesis of DED is …

… In the present study, we investigated the role of memory Th17 cells in DED pathogenesis
in aged mice. Specifically, DED severity was evaluated in young (6- to 8-week–old) versus …

… mice in our experiments showed higher percentage of Th17 cells in … of Th17 cells in draining
lymph nodes and decreased expression of IL-17A in conjunctiva were observed in dry eye …

… factors in the pathogenesis of dry eye disease, as suggested by the well-known role between
the … Th17 cells antagonize regulatory T cell (Treg) function, and the resulting dysfunctional …