Reducing VEGFB expression regulates the balance of glucose and lipid metabolism in mice via VEGFR1

X Luo, RR Li, YQ Li, HP Yu… - Molecular …, 2022 - spandidos-publications.com
… tolerance tests and glucose tolerance tests, and function of β‑cell islets was evaluated by
using the insulin resistance index (HOMA‑IR) and pancreatic β‑cell secretion index (HOMA‑β). …

VEGF-A/VEGFR-2 and FGF-2/FGFR-1 but not PDGF-BB/PDGFR-β play important roles in promoting immature and inflammatory intraplaque angiogenesis

Y Mao, X Liu, Y Song, C Zhai, L Zhang - PLoS One, 2018 - journals.plos.org
… Therefore, in the present study, inflammation might be another cause of the release of
VEGF-A and for the positive relationship between TNF-α and VEGF-A/VEGFR-2, FGF-2/FGFR-1. …

Adrb2 controls glucose homeostasis by developmental regulation of pancreatic islet vasculature

AM Ceasrine, EE Lin, DN Lumelsky, R Iyer, R Kuruvilla - Elife, 2018 - elifesciences.org
… , β-cells elicited metabolic defects in mice, supporting a critical role for β-cell Adrb2 during
development. We provide evidence that Adrb2 acts in β-cells to suppress VEGF-A expression …

[HTML][HTML] Vascular endothelial growth factor over-expressed mesenchymal stem cells-conditioned media ameliorate palmitate-induced diabetic endothelial dysfunction …

T Xu, Z Lv, Q Chen, M Guo, X Wang, F Huang - Biomedicine & …, 2018 - Elsevier
… Moreover, endothelial cells maintain beta cells function and promote their proliferation and
differentiation in adults through paracrine effect [5], particularly by secreting some endothelial …

Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets

LA Llacua, MM Faas, P de Vos - Diabetologia, 2018 - Springer
… More specifically, some ECM molecules are involved in beta cell survival, function and …
) in beta cells, a receptor that regulates pathways involved in beta cell survival and function [20]. …

NDRG1 activates VEGF-A-induced angiogenesis through PLCγ1/ERK signaling in mouse vascular endothelial cells

K Watari, T Shibata, H Fujita, A Shinoda… - Communications …, 2020 - nature.com
… the essential role of NDRG1 in ECs in response to the potent angiogenic factor VEGF-A,
we … Here, to our knowledge, we present the specific and novel role of NDRG1 in VEGF-A-…

Pancreatic alpha-cells contribute together with beta-cells to CXCL10 expression in type 1 diabetes

L Nigi, N Brusco, GE Grieco, G Licata… - Frontiers in …, 2020 - frontiersin.org
pancreatic endocrine cell subtypes has not been clarified yet. Therefore, the purpose of this
study was to shed light on the pancreatic … of VEGF-A (56). Angiogenesis has been linked to …

Heparanase regulates in vitro VEGF-C expression and its clinical significance to pancreatic ductal cell adenocarcinoma

B Lv, B Zhang, XY Hu, QD Zeng - Oncology Letters, 2016 - spandidos-publications.com
VEGF-A predominantly promotes angiogenesis through interactions with VEGF receptor-1,2
(VEGFR-1,2), whereas VEGF-C induces lymphangiogenesis by attaching to VEGF receptor-…

[HTML][HTML] VEGF-A and VEGF-B coordinate the arteriogenesis to repair the infarcted heart with vagus nerve stimulation

Y Lv, S Zhong, H Tang, B Luo, SJ Chen… - Cellular Physiology and …, 2018 - karger.com
… gene therapy does not lead to an increased angiogenesis or improved heart function [20], …
found that mainly VEGF-A and VEGF-B were induced in vascular smooth muscle cells (VSMCs…

Determination of VEGFR-2 (KDR) 604A> G polymorphism in pancreatic disorders

V Pădureanu, MV Boldeanu, I Streaţă… - International Journal of …, 2017 - mdpi.com
… VEGF family consists of several members: VEGF-A, PlGF (placental growth factor), VEGF-B, …
KDR binds VEGF-A, VEGF-C and VEGF-D, this proteins playing a role in the regulation of …