… role in blocking allergen-induced inflammation, but not in the cell death process of hyperplastic
airway epithelial cells… shRNA enhanced IFN-γ-induced NF-κB activity in cells treated with …

… (emphysema) and small airway remodeling in chronic models. … bronchial epithelial cells
from smoke-mediated apoptosis by … behind IFN-γ induced emphysema pathophysiology [155]. …

… Regardless of potent cathepsin B inhibition, no cell death … in IFN-γ induced cathepsin S
expression in infected cells. On … 10 induction to block cathepsin S dependent processing of Ii in …

… Because the current reported studies on the molecular action of IFN-γ in tumor cells are …
the modulation of IFN-γ-induced effects on HNSCC cells. IFNγ coordinates cellular functions via …

… mucosal inflammation and tissue remodeling. Transcriptional … and epithelial cells and
examine functional significance in … These studies implicate IFN-γ-induced epithelial dysfunction …

… airway disease that presents with different types and degrees of inflammation often in
association with airway … and/or neutrophils and resident airway structural cells participate in the …

… that affect a range of lung cells including immune cells and airway epithelial cells. The …
Repeated injury to the lung epithelial barrier through both smoking and IFN-γ-induced apoptosis, …

… of an endogenous process leading to alveolar destruction and remodeling, and finally a …
alveolar epithelial cell death and activation of extracellular matrix proteases, such as cathepsin …

… Cathepsin S-dependent epithelial cell apoptosis is a crucial event in the pathogenesis of
IFN-γ-induced alveolar … The fate of lung alveolar cells in emphysema is shown in Fig. 38.3. …

… active enzymes in cells and tissues. As proteases serve as key marker proteins for a variety
of physiological and pathological processes, such as tissue remodeling, apoptosis, fibrosis, …