… which results in an unfavorable titin isoform ratio and progression of diastolic dysfunction. In
summary, estrogen can modulate diastolic function by controlling the level of titin isoforms, a …

… pathway in diastolic dysfunction induced by OVX in mRen2.Lewis rats. Estrogen receptor …
into pharmaceutical strategies for treating diastolic dysfunction in postmenopausal women. …

… stiffness and compliance, respectively (19), we hypothesized that diastolic dysfunction in
female ERαMut is mediated through myocardial stiffening contributed by a greater degree of …

… We hypothesized that estrogen receptor (ER) signaling plays a direct role in regulation of
autophagy and mitophagy-mediated maintenance of muscle mass and muscle mitochondrial …

… diastolic function in both women and men; hence, female reproductive factors may accelerate
diastolic … It is likely that the loss of estrogens due to the menopausal transition contributes …

… and diastolic dysfunction, an important precursor to HFpEF. … to RV hypertrophy displayed
diastolic dysfunction as well as an … diastolic dysfunction may be sex-specific in nature [113]. …

… Investigation on the cardiovascular role of estrogen receptors (ER) has recently … of estrogen
deficiency in pathological processes, such as immune cell activation, endothelial dysfunction…

… Estrogen deficiency in postmenopausal … LV diastolic dysfunction (LVDD) and HFpEF, as
estrogen influences a number of biological processes that have been implicated as having roles …

… The goal of our study was to assess the prevalence of left ventricular diastolic dysfunction
(LVDD) among diabetic women (DW) and its correlation with glycosylated hemoglobin (HbA 1c…

… These findings suggest that the loss of the cardioprotective effect of estrogen after menopause
may play an important role in the deterioration of LVDD in elderly women [11]. However, …