… of αvβ3-integrin in tumour angiogenesis. Learning from what we now know about integrin …
discuss the possible future of targeting blood vessel αvβ3-integrin in the control of cancer. …

… 3 integrin … integrin following MI using the novel α v β 3 integrin-selective radiotracer, 18
F-fluciclatide, combined with cardiac positron emission tomography (PET), CT and cardiovascular …

… Despite the fact that all the former integrins have been implicated in angiogenesis, this
section will only focus on those having a central role in tumor angiogenesis, namely: αvβ3, αvβ5 …

… -3 induces vascular fibrosis are still unclear. We studied the role of integrin αv in Ang II-induced
VSMCs arterial fibrosis and stiffness via a SMC specific knock-out of integrin αv mouse …

… antagonists that interact with integrin αvβ3 could revert the TGF-β1-… integrin β3 may play an
important role in endothelial transdifferentiation. We found that AVF patients had high integrin …

… Lastly, we will review roles for integrins in vascular … focus on αv integrin adhesion and
signaling functions in the malignant … αvβ8, αvβ3, and αvβ5 integrins are known to be upregulated …

… , due to the lack of FN–ECM and its canonical integrin … biological mechanisms elicited by
the αvβ3 integrin in fibroblasts derived from patients affected with classical (cEDS), vascular (…

… of αvβ3 integrin blocking upon treatment with DisBa-01. Due to the essential role of the αvβ3
integrin … of the tumor and endothelial cells upon αvβ3 integrin blockade, depending on the …

… Upregulated expression of αvβ3 promoted blood vessel formation … suppressor in CC through
integrin αvβ3, which provides a … provide evidence supporting the role of integrin αvβ3 in the …

… and αvβ3-specific antagonists, RGD peptide, or integrin blocking … Previous preclinical and
clinical studies emphasizing αvβ3 … the role of other integrins in SMC biology could lead to new …