MaterialDriven Fibronectin Assembly Promotes Maintenance of Mesenchymal Stem Cell Phenotypes

P Rico, H Mnatsakanyan, MJ Dalby… - Advanced Functional …, 2016 - Wiley Online Library
… we have termed material-driven fibronectin fibrillogenesis.22-… role of FN nanonetworks on
MSC adhesion, differentiation (… evaluation of results obtained for cell differentiation on the FN-…

Material-driven fibronectin assembly for high-efficiency presentation of growth factors

V Llopis-Hernández, M Cantini, C González-García… - Science …, 2016 - science.org
material-driven FN fibrillogenesis provides synergistic integrin/BMP-2 signaling that drives
osteoblastic differentiation in primary human mesenchymal stem cells … of cell differentiation. …

[HTML][HTML] Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis

Y Xiao, H Donnelly, M Sprott, J Luo, V Jayawarna… - Materials Today Bio, 2022 - Elsevier
… exploit ECM proteins to reveal cell adhesion and GF binding sites, … for controlling stem cell
differentiation and improving the … It is of note that cells are not able to drive FN fibrillogenesis

Cell migration on material-driven fibronectin microenvironments

E Grigoriou, M Cantini, MJ Dalby, A Petersen… - Biomaterials …, 2017 - pubs.rsc.org
Fibronectin (FN) is the main component of the ECM and it modulates several cell processes,
such as adhesion, differentiation … do or don't drive FN fibrillogenesis. This new work aims at …

Fibronectin-enriched biomaterials, biofunctionalization, and proactivity: a review

C Palomino-Durand, E Pauthe, A Gand - Applied Sciences, 2021 - mdpi.com
… been shown to induce Fn fibrillogenesis, a process usually driven by cells, leading to the …
stiffness (~55 kPa) led to cell differentiation into the osteoblastic phenotype associated with a …

[HTML][HTML] Role of chemical crosslinking in material-driven assembly of fibronectin (nano) networks: 2D surfaces and 3D scaffolds

RS i Serra, L León-Boigues, A Sánchez-Laosa… - Colloids and Surfaces B …, 2016 - Elsevier
… to as material-driven fibronectin fibrillogenesis. As consequence of protein-material interactions,
a physiological-like FN (nano)network is organised upon simple adsorption of FN from a …

[HTML][HTML] Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts

EN Mpoyi, M Cantini, YY Sin, L Fleming, DW Zhou… - Biomaterials, 2020 - Elsevier
… and other collagens and regulates cell adhesion, differentiation, migration and proliferation
[… aspects of cell-mediated FN fibrillogenesis [35,36]. This material-driven FN matrix also …

Vitronectin as a micromanager of cell response in materialdriven fibronectin nanonetworks

M Cantini, K Gomide, V Moulisova… - Advanced …, 2017 - Wiley Online Library
… the level of cell fusion and the degree of cell differentiation. … adsorption of fibronectin and
vitronectin fine-tune cell behavior… the effect of VN on material-driven FN fibrillogenesis, by co-…

The role of fibronectin in mediating cell migration

JH Longstreth, K Wang - … Journal of Physiology-Cell …, 2024 - journals.physiology.org
… ); however, FN fibrillogenesis 129 in neural crest cells occurs on a … fibronectin fragment FN-
652 CH296 to stimulate T-cells for … T-cells yielded a less differentiated phenotype that is more …

[HTML][HTML] Engineering fibronectin-templated multi-component fibrillar extracellular matrices to modulate tissue-specific cell response

S Ahn, A Jain, KC Kasuba, M Seimiya, R Okamoto… - Biomaterials, 2024 - Elsevier
… Here, we introduce the engineering of fibrillar fibronectin-… employed their innate fibrillogenic
mechanisms including shear … roles in neuronal proliferation, migration, and differentiation […