[PDF][PDF] Modulation of Apoptosis Pathways in the Biology and Treatment of Multiple Myeloma
… as a result of genetic changes during differentiation of B cells … (FAS/Apo-1), DR3, TNF-R1
and two TNF-related apoptosis… TRAIL-induced apoptosis in multiple myeloma cells is also …
and two TNF-related apoptosis… TRAIL-induced apoptosis in multiple myeloma cells is also …
[HTML][HTML] Apoptosis evasion via long non-coding RNAs in colorectal cancer
… proliferation, differentiation and death of cancer cells [9]. The … The p53 the best-known tumor
suppressor is involved in the … plays a significant role in TRAIL-induced apoptosis. P38 brings …
suppressor is involved in the … plays a significant role in TRAIL-induced apoptosis. P38 brings …
The importance of p53 pathway genetics in inherited and somatic cancer genomes
… p53-mediated tumour suppression in humans and into p53 … 3; PERP, TP53 apoptosis
effector; PIDD, p53-induced death … SNPs and the noted differential cancer risk, we could expect …
effector; PIDD, p53-induced death … SNPs and the noted differential cancer risk, we could expect …
Oncogenic mutant p53 gain of function nourishes the vicious cycle of tumor development and cancer stem-cell formation
Y Shetzer, A Molchadsky… - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
… p53 may be regarded as a proto-oncogene tumor suppressor… mut-p53-expressing iPSCs
were able to differentiate into the … inducing apoptosis and activating several p53 target genes …
were able to differentiate into the … inducing apoptosis and activating several p53 target genes …
Dysfunctional diversity of p53 proteins in adult acute myeloid leukemia: projections on diagnostic workup and therapy
M Prokocimer, A Molchadsky… - Blood, The Journal of the …, 2017 - ashpublications.org
… to display differential susceptibility to p53-targeted therapies. … that TP53-R72 is more
effective at inducing cell death and … -induced repression of the proapoptotic CD95 (Fas/Apo-1), …
effective at inducing cell death and … -induced repression of the proapoptotic CD95 (Fas/Apo-1), …
Inhibition of p53 inhibitors: progress, challenges and perspectives
… restore the tumor suppressor function of wild-type p53 and … 1), the structural differences in
the p53-binding pocket between these … can also induce apoptosis in p53-deficient cancer cells …
the p53-binding pocket between these … can also induce apoptosis in p53-deficient cancer cells …
[HTML][HTML] Apoptosis and genes involved in oral cancer-a comprehensive review
… protein (SIVA) inducing apoptosis. Binding of CD27 to its ligand causes T cell activation,
differentiation, and survival thus … TP53 gene (17p13.1) a tumor suppressor gene, codes for …
differentiation, and survival thus … TP53 gene (17p13.1) a tumor suppressor gene, codes for …
The sumoylation modulated tumor suppressor p53 regulates cell cycle checking genes to mediate lens differentiation
X Tang, Z Chen, M Deng, L Wang, Q Nie… - Current molecular …, 2018 - ingentaconnect.com
… that p53-Bak signaling axis plays an important role in mediating EGCG-induced apoptosis.
… Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol …
… Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol …
Induction of apoptosis in leukemic cells by the alkaloid extract of garden cress (Lepidium sativum L.)
SS Basaiyye, S Kashyap, K Krishnamurthi… - Journal of Integrative …, 2019 - Elsevier
… The difference between control and treated cells was … The 2.2- and 1.8-fold upregulation
of tumor suppressor genes p53 … 27 blocks Fas/APO-1- and staurosporine-induced cell death …
of tumor suppressor genes p53 … 27 blocks Fas/APO-1- and staurosporine-induced cell death …