Correlation between endogenous polyamines in human cardiac tissues and clinical parameters in patients with heart failure

C Meana, JM Rubin, C Bordallo… - Journal of cellular …, 2016 - Wiley Online Library
… of enzyme activity was defined as 1 nmol H 2 O 2 formed per … ODC activity (which converts
ornithine into putrescine) 36 … mechanism to preserve cardiac contractility. These associations …

[HTML][HTML] Putrescine promotes MMP9-induced angiogenesis in skeletal muscle through hydrogen peroxide/METTL3 pathway

C Hu, F Ji, R Lv, H Zhou, G Hou, T Xu - Free Radical Biology and Medicine, 2024 - Elsevier
… Inhibition of putrescine formation by DFMO led to the up-regulated the hydrogen peroxide
… with angiogenesis and polyamine metabolic processes. Further investigation revealed that …

Polyamines and heart physiology

CM Caldarera, F Flamigni, C Rossoni… - The Physiology of …, 2021 - taylorfrancis.com
… for this interconversion process, arerather low in rat heart;41 •… into putrescine; however, the
formation of putrescine via this … the metabolic and contractile activity of the heart cell closely …

[HTML][HTML] Histamine can be Formed and Degraded in the Human and Mouse Heart

J Neumann, JM Grobe, J Weisgut… - Frontiers in …, 2021 - frontiersin.org
… This process can be enhanced by histamine and blocked by … in supernatants with 14 C-putrescine
(300 μM) as substrate. … : 10 mM histidine increased force of contraction by 27% from …

Beneficial effects of spermidine on cardiovascular health and longevity suggest a cell type-specific import of polyamines by cardiomyocytes

BO Nilsson, L Persson - Biochemical Society Transactions, 2019 - portlandpress.com
process which is thought to be temperature-dependent but Na + -independent [9,10]. For
putrescine… polyamine formation, assessed by measuring ODC activity, is higher in the immature …

[HTML][HTML] Cardiac surgery with crystalloid cardioplegia: improved functional recovery due to molecular adaptations in adult rat hearts

A Boening, T Attmann, M Heep… - Research in …, 2017 - journals.lww.com
… maintenance of contractile activity, proper formation of cell–… out according to the 2 −ΔΔCt
methods as described.[ 6 ] After … of putrescine on the functional recovery of rat hearts exposed …

The calcium-sensing receptor in heart physiology and development of endothelin-1-dependent hypertrophy

E Dyukova - 2016 - jlupub.ub.uni-giessen.de
… and differentiation processes in tissue specific manner. … Effects of putrescine on atrial
contraction force d. Spermine … Along with increased IP3 formation, there is parallel enhanced DAG …

Gasdermin D deficiency in vascular smooth muscle cells ameliorates abdominal aortic aneurysm through reducing putrescine synthesis

J Gao, Y Chen, H Wang, X Li, K Li, Y Xu… - Advanced …, 2023 - Wiley Online Library
… and increase susceptibility to Ang II-induced AAA formation in … , putrescine affected the
switch of VSMCs from contractile to … microscopy or other methods. Transmission electron …

[HTML][HTML] Modulatory effect of intestinal polyamines and trace amines on the spontaneous phasic contractions of the isolated ileum and colon rings of mice

M Sánchez, L Suárez, MT Andrés, BH Flórez… - Food & nutrition …, 2017 - Taylor & Francis
… (PDGFR)-positive cells, forming a functional electrical syncytium, … of contraction to ACh,
contrary to the potentiation of putrescine and spermine reported on carbachol-elicited contraction

Physiological importance of polyamines

YY Lenis, MA Elmetwally, JG Maldonado-Estrada… - Zygote, 2017 - cambridge.org
… Histotroph is formed by molecules such as: amino acids, … endometrial and placental
functions, muscle contraction, and … showed a greater effect of putrescine for reversing the effects …