[HTML][HTML] Membrane interactivity of capsaicin antagonized by capsazepine
M Mizogami, H Tsuchiya - International Journal of Molecular Sciences, 2022 - mdpi.com
… whether capsaicin and its antagonist capsazepine interact … analogy of drug–receptor
interaction, capsazepine is likely to … When administered to a rat tail and spinal cord, capsazepine …
interaction, capsazepine is likely to … When administered to a rat tail and spinal cord, capsazepine …
[HTML][HTML] The mysteries of capsaicin-sensitive afferents
… , the capsaicin receptor turned out to be a transient receptor … TRPV1 antagonists, capsazepine
and BCTC. The advent of … is little evidence for non-specific, TRPV1-independent capsaicin …
and BCTC. The advent of … is little evidence for non-specific, TRPV1-independent capsaicin …
[HTML][HTML] Beneficial effects of capsaicin in disorders of the central nervous system
M Pasierski, B Szulczyk - Molecules, 2022 - mdpi.com
… capsaicin could be detected in the plasma, brain, and spinal … , TRPV1 antagonist capsazepine
applied without capsaicin … presented evidence that capsaicin activated TRPV1 receptors…
applied without capsaicin … presented evidence that capsaicin activated TRPV1 receptors…
Modelling of the binding of TRPV1 receptor to capsaicin, capsazepine and related agonists and antagonists
B İnce - 2019 - acikbilim.yok.gov.tr
… TRPV1 is a non-selective receptor located in dorsal ganglia. It is also distributed in brain
tissue… This is the most direct evidence acquired by experiments for capsaicin binding location in …
tissue… This is the most direct evidence acquired by experiments for capsaicin binding location in …
[HTML][HTML] Capsaicin, the vanilloid receptor TRPV1 agonist in neuroprotection: mechanisms involved and significance
OME Abdel-Salam, G Mózsik - Neurochemical Research, 2023 - Springer
… studies provided evidence that capsaicin protected against … resiniferatoxin binding sites
from rat spinal cord [18, 19]. … be prevented by the TRPV1 receptor antagonist capsazepine [33]. …
from rat spinal cord [18, 19]. … be prevented by the TRPV1 receptor antagonist capsazepine [33]. …
[HTML][HTML] Use of capsaicin to treat pain: mechanistic and therapeutic considerations
MK Chung, JN Campbell - Pharmaceuticals, 2016 - mdpi.com
… that the TRPV1 receptor in birds is capsaicin-insensitive [5]. … , evidence exists to indicate
that injection of capsaicin decreases … prevented by capsazepine [95] or a specific antagonist of …
that injection of capsaicin decreases … prevented by capsazepine [95] or a specific antagonist of …
[HTML][HTML] Control of sensory neuron excitability by serotonin involves 5HT2C receptors and Ca2+-activated chloride channels
I Salzer, E Gantumur, A Yousuf, S Boehm - Neuropharmacology, 2016 - Elsevier
… by this CaCC blocker and by the TRPV1 inhibitor capsazepine. Amongst the subtype …
Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin…
Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin…
[HTML][HTML] Constitutive activity of transient receptor potential vanilloid type 1 triggers spontaneous firing in nerve growth factor-treated dorsal root ganglion neurons of …
N Kitamura, E Nagami, Y Matsushita, T Kayano… - IBRO reports, 2018 - Elsevier
… Based on the evidence that I sp was blocked by tetrodotoxin (a blocker of … capsaicin currents
significantly. Therefore, we concluded that capsazepine and BCTC are suitable antagonists …
significantly. Therefore, we concluded that capsazepine and BCTC are suitable antagonists …
Medicinal chemistry, pharmacology, and clinical implications of TRPV1 receptor antagonists
M Aghazadeh Tabrizi, PG Baraldi… - Medicinal research …, 2017 - Wiley Online Library
… Further evidences supporting the role of TRPV1 in pain … in the alimentary canal is in
spinal and vagal primary afferent … has been shown that capsazepine blocked capsaicin-mediated …
spinal and vagal primary afferent … has been shown that capsazepine blocked capsaicin-mediated …
[HTML][HTML] Capsaicin, nociception and pain
B Frias, A Merighi - Molecules, 2016 - mdpi.com
… provided further evidence that the receptor was activated by capsaicin, … antagonist
capsazepine in WT mice significantly inhibits esophagitis [152]. In cat spinal afferents, capsaicin-…
capsazepine in WT mice significantly inhibits esophagitis [152]. In cat spinal afferents, capsaicin-…