Recent trends of self-emulsifying drug delivery system for enhancing the oral bioavailability of poorly water-soluble drugs

P Tran, JS Park - Journal of pharmaceutical Investigation, 2021 - Springer
… Depending on the preparation procedure, drug-loaded … review, we summarize the classification
system of lipid formulations, the mechanism underlying improved oral drug absorption by …

Improving The oral absorption of nintedanib by a self-microemulsion drug delivery system: preparation and in vitro/in vivo evaluation

H Liu, J Mei, Y Xu, L Tang, D Chen, Y Zhu… - International Journal …, 2019 - Taylor & Francis
improving the oral bioavailability of nintedanib. Self-microemulsifying drug delivery systems
… stability are considered ideal alternative oral drug delivery carriers for drugs with poor …

Can APIs that are Poorly Water‐and Oil‐Soluble Benefit from Incorporation into SMEDDS? The Case of Dipyridamole

K Rede, K Bolko Seljak, M Bogataj… - European Journal of …, 2021 - Wiley Online Library
self-microemulsifying drug delivery system (SMEDDS) for the model active pharmaceutical
ingredient (API) dipyridamole using exclusively excipients suitable for oral administration and …

Self-nanoemulsifying drug delivery system: A versatile carrier for lipophilic drugs

D Singh - Pharmaceutical Nanotechnology, 2021 - ingentaconnect.com
… In vitro dissolution assay indicated that dipyridamole in SNEDDS dissolved rapidly, while …
opment of self-microemulsifying drug delivery systems for oral bioavailability enhancement of …

Self-emulsifying drugdelivery systems modulate P-glycoprotein activity: Role of excipients and formulation aspects

K AboulFotouh, AA Allam, M El-Badry… - Nanomedicine, 2018 - Future Medicine
… ‘self-microemulsifying drugdelivery systems’ (SMEDDS). Since, by definition, microemulsions
are formed spontaneously, the term ‘SMEDDS’ is meaningless [50]. On the other hand, …

Development and evaluation of dipyridamole sustained release tablets containing micro-environmental pH modifiers

Z Xi, N Sharma, A Paprikar, S Lin - … Drug Delivery Science and Technology, 2019 - Elsevier
… study is to develop sustained release of dipyridamole, a poorly soluble weakly basic compound.
The solubility of dipyridamole is the limit step of its bioavailability. To improve this, direct …

A Comprehensive Insight on Self Emulsifying Drug Delivery Systems

R Kadian, A Nanda - Recent Advances in Drug Delivery and …, 2022 - ingentaconnect.com
… Type III formulations are also known as self microemulsifying drug delivery systems. These
kinds of formulations can be further categorized into two types, named type III A and type III B. …

Dipyridamole cocrystal tablets with enhanced solubility and dissolution at intestinal pH

M Nijhawan, S Dhyagala, S Gunnam… - … of Pharmaceutical …, 2024 - dergipark.org.tr
… Aim of the study was to prepare dipyridamole (DPM) cocrystals to alter its physicochemical
properties as it is poorly soluble in water, 6.8 pH buffer and belongs to BCS class II. …

Development and in vitro/in vivo performance of self-nanoemulsifying drug delivery systems loaded with candesartan cilexetil

K AboulFotouh, AA Allam, M El-Badry… - … of Pharmaceutical …, 2017 - Elsevier
enhance the oral bioavailability of candesartan cilexetil by presenting the drug in a pre-solubilized
form ready for absorption… inhibition potential to enhance its oral delivery. Also, the …

[PDF][PDF] Formulation and Development of Gastroretentive Dipyridamole Microspheres: Proof of Concept by In vitro-In vivo Assessment.

SD Vanshiv, HP Joshi, AB Aware - … Journal of Pharmaceutical …, 2018 - researchgate.net
… The present research was aimed at development and optimization of dipyridamoleSelf-microemulsifying
drug delivery system for improved oral bioavailability of dipyridamole: …