Tamoxifen and the PI3K inhibitor: LY294002 synergistically induce apoptosis and cell cycle arrest in breast cancer MCF-7 cells
… In order to elucidate the underlying mechanism of the synergistic inhibition of BC cell growth
by LY and TAM combination, apoptosis analysis was performed through annexin V FITC/PI …
by LY and TAM combination, apoptosis analysis was performed through annexin V FITC/PI …
ER-α36, a novel variant of ERα, is involved in the regulation of Tamoxifen-sensitivity of glioblastoma cells
Y Liu, L Huang, X Guan, H Li, QQ Zhang, C Han… - Steroids, 2016 - Elsevier
… benefits when treating glioblastoma via a sensitization of tumor cells to radiotherapy and an
… evidence has shown that TAM induces apoptosis in glioblastoma cells via the PI3k/Akt, JNK …
… evidence has shown that TAM induces apoptosis in glioblastoma cells via the PI3k/Akt, JNK …
Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells
T Shingu, L Holmes, V Henry, Q Wang, K Latha… - Journal of translational …, 2016 - Springer
… Glioma cells that are resistant to cell death-inducing stimuli … treatments using RTK inhibitors,
non-receptor kinase inhibitors… difficulty in predicting sensitivity of glioma cells to specific …
non-receptor kinase inhibitors… difficulty in predicting sensitivity of glioma cells to specific …
CSC-3436 switched tamoxifen-induced autophagy to apoptosis through the inhibition of AMPK/mTOR pathway
ST Wu, GH Sun, TL Cha, CC Kao, SY Chang… - Journal of biomedical …, 2016 - Springer
… eg glioma, melanoma, colon cancer and pancreatic carcinoma though growth … tamoxifen
induced cytoptotective role in TNBC cells. Interestingly, CSC-3436 sensitized TNBC cells …
induced cytoptotective role in TNBC cells. Interestingly, CSC-3436 sensitized TNBC cells …
[PDF][PDF] Sensitizer drugs for the treatment of temozolomide-resistant glioblastoma
A Baritchii, A Jurj, O Soritau, C Tomuleasa, L Raduly… - J buon, 2016 - jbuon.com
… Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor
through the GSK-3β/β-catenin signaling pathway. PLoS One 2011;6(10):e27053. 31. …
through the GSK-3β/β-catenin signaling pathway. PLoS One 2011;6(10):e27053. 31. …
[PDF][PDF] ERK1/2 ź ͨ· Tamoxifen ½ ϸ Ӱ
T Fen, WU Hui-jiao, XIE Fu-kang, LI Chao-hong - ѧ о - smkx.hunnu.edu.cn
… Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through
the … Tamoxifen-induced apop原 tosis of rat C6 glioma cells via PI3K/Akt, JNK and ERK acti原 …
the … Tamoxifen-induced apop原 tosis of rat C6 glioma cells via PI3K/Akt, JNK and ERK acti原 …
[HTML][HTML] Huaier extract synergizes with tamoxifen to induce autophagy and apoptosis in ER-positive breast cancer cells
W Qi, M Sun, X Kong, Y Li, X Wang, S Lv, X Ding… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… During autophagic cell death, portions of the cytoplasm are sequestered into double
membrane vesicles known as autophagosomes, which then fuse with lysosomes to form single-…
membrane vesicles known as autophagosomes, which then fuse with lysosomes to form single-…
Volatile Oil of Acori Graminei Rhizoma-Induced Apoptosis and Autophagy are dependent on p53 Status in Human Glioma Cells
L Chen, Z Jiang, H Ma, L Ning, H Chen, L Li, H Qi - Scientific Reports, 2016 - nature.com
… autophagy during induction of cancer cell death, which is a process naturally regarded as
… consumes cellular components and generates energy, it may sensitize cells to apoptosis by …
… consumes cellular components and generates energy, it may sensitize cells to apoptosis by …
Tamoxifen and oxidative stress: an overlooked connection
… MAP kinase in glioma C6 cells [80]. Tamoxifen induces … with inhibition of tamoxifen-induced
apoptosis, whereas deletion of a calmodulin-binding domain on c-FLIP restored sensitivity to …
apoptosis, whereas deletion of a calmodulin-binding domain on c-FLIP restored sensitivity to …
Loss of PKCδ induces prostate cancer resistance to paclitaxel through activation of Wnt/β-Catenin pathway and Mcl-1 accumulation
ML Flores, C Castilla, J Gasca, R Medina… - Molecular cancer …, 2016 - AACR
… to improve the sensitivity to taxanes in the absence of PKCδ. … determine the sensitivity to
apoptosis during mitotic arrest … In accordance with data published in glioma cells (24), we …
apoptosis during mitotic arrest … In accordance with data published in glioma cells (24), we …