… of a lncRNA–miRNA–mRNA competing endogenous RNA network from inflamed and normal synovial tissues after anterior cruciate ligament and/or meniscus injuries

X Xiao, X Yang, S Ren, C Meng, Z Yang - Frontiers in Genetics, 2022 - frontiersin.org
… are associated with posttraumatic osteoarthritis (PTOA) … after knee injury, which might be
related to the progression of … in this study provide potential biomarkers for PTOA diagnosis, …

Unraveling the Molecular Landscape of Osteoarthritis: A Comprehensive Review Focused on the Role of Non-Coding RNAs

M Shakeri, A Aminian, K Mokhtari, M Bahaeddini… - … -Research and Practice, 2024 - Elsevier
… This review delves into the emerging molecular biomarkers in OA pathology, … RNAs (ncRNAs),
including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), and circular RNAs

The emerging role of non-coding RNAs in osteoarthritis

S Ghafouri-Fard, C Poulet, M Malaise, A Abak… - Frontiers in …, 2021 - frontiersin.org
… (in blood/plasma/serum) are definitely one of the most interesting biomarkers for OA due to
… for this purpose, blood/plasma/serum samples are superior since they are obtained through …

[HTML][HTML] Utility of circulating serum miRNAs as biomarkers of early cartilage degeneration in animal models of post-traumatic osteoarthritis and inflammatory arthritis

LHW Kung, S Zaki, V Ravi, L Rowley, MM Smith… - Osteoarthritis and …, 2017 - Elsevier
… miRNAs are a family of evolutionarily-conserved small non-coding RNAs, with more than …
assayed serum from patients with and without cartilage damage 1 year post ACL injury and …

[HTML][HTML] Soluble biomarkers in osteoarthritis in 2022: year in review

FAC Rocha, SA Ali - Osteoarthritis and Cartilage, 2023 - Elsevier
… of biomarkers for OA, namely non-coding RNAs. … non-coding RNAs analyzed 84 lncRNAs
in serum from knee OA patients and assessed pain intensity before and 1 year after total knee

Circulating long non-coding RNA signature in knee osteoarthritis patients with postoperative pain one-year after total knee replacement

R Giordano, KK Petersen, M Santoro… - … Journal of Pain, 2021 - degruyter.com
… The coagulated blood was removed centrifuging at 3,000 RPM for 15 min and the serum
eight lncRNA biomarkers in patients with osteoarthritis (OA) of the knee associated with mild …

Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis

MMF Steinbusch, Y Fang, PI Milner, PD Clegg… - Scientific reports, 2017 - nature.com
non-coding RNAs whose length is a hundred bp and over. In contrast, a peak is presented at
30 bp long for serum … , enabling distinction between ACL injury patients from normal donors…

The non-coding RNA interactome in joint health and disease

SA Ali, MJ Peffers, MJ Ormseth, I Jurisica… - Nature Reviews …, 2021 - nature.com
… In osteoarthritis and rheumatoid arthritis, non-coding RNAs … than in the serum 31 ) or other
mechanisms of non-coding RNA … In addition to their roles as biomarkers, non-coding RNAs in …

185 IDENTIFICATION OF SMALL NON-CODING RNAS IN CANINE ANTERIOR CRUCIATE LIGAMENT DISEASE AS DIAGNOSTIC MARKERS AND FUTURE …

Y Ashraf-Kharaz, R Mullins, P Muir… - Osteoarthritis and …, 2024 - oarsijournal.com
ACL injury and dogs undergoing ACL reconstruction surgery. Total RNA was extracted from
ACLs … We have identified a panel of potential biomarkers which could be used to enable …

MicroRNAs and long non-coding RNAs in cartilage homeostasis and osteoarthritis

J Gu, W Rao, S Huo, T Fan, M Qiu, H Zhu… - Frontiers in Cell and …, 2022 - frontiersin.org
… and the disease progression of OA. … the progression of OA through distinct molecular
mechanisms. Recent studies highlighted the potential of ncRNAs to serve as diagnostic biomarkers, …