… to the stress of severe injury or infection, hindering recovery (7–10). … events of cortisol found
that CFS/ME patients have the same … Without excluding possible predisposing genetic or …

… Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic debilitating disease
characterized by severe … patients and 12 recovered controls were available for follow-up …

… with myalgic encephalomyelitis/chronic fatigue syndrome (ME/… likely to have ceased
employment due to their illness [11]. … Also, the fatigue severity score remained the same (26), and …

… of recovery in paediatric CFS/ME, the rate of recovery and … most severely affected by
CFS/ME with a worse prognosis.3 … are likely to be crucial in developing a definition of recovery …

… Instead, we propose that recovery is often possible if patients are … Severe, persistent fatigue
conditions are a pressing public … The narrative of CFS/ME as an incomprehensible and …

… (moderate) or bedridden (severe), and the very severely ill who are completely dependent on
… metabolic adaptations aiming to restore energy supply. Possible strategies for clinical trials …

… severe symptoms; and, in the presence of psychiatric co-morbidity. A subsequent systematic
review on prognosis found a median recovery … are likely to be severe, with profound fatigue, …

… , although improvement would be more difficult for more severe patients. Participant 3, believed
… Only Physician 8 believed recovery was likely in younger patients, but less likely in older …

… , fatigue features, post-exertional malaise severity, clinical … are less likely to experience
spontaneous recovery [14] and more … The data presented in this study are available on request …

… and rehabilitation therapy programs may be of benefit for CFS/ME… characterized by an extreme
disabling fatigue that does not … of the pharmacological interventions available in CFS/ME. …