Inflammation and colorectal cancer
AG Long, ET Lundsmith, KE Hamilton - Current colorectal cancer reports, 2017 - Springer
… Cross-talk among these cell types is predominantly through a network of cytokines,
chemokines, and other growth factors. Specific signaling of these secreted factors is dependent on …
chemokines, and other growth factors. Specific signaling of these secreted factors is dependent on …
[HTML][HTML] Kidins220 and tumour development: Insights into a complexity of cross-talk among signalling pathways
… and its role in cancer development. Further investigation is … its implication in tumourigenesis
and cancer progression. … sites, through which Kidins220 coordinates signal transduction of …
and cancer progression. … sites, through which Kidins220 coordinates signal transduction of …
Interaction of the Wnt/β-catenin and RAS-ERK pathways involving co-stabilization of both β-catenin and RAS plays important roles in the colorectal tumorigenesis
… the current understanding of cross-talk between Wnt/β-catenin … The highlight of the cross-talk
is the stabilizations of both β-… KRAS mutations in colorectal tumorigenesis including initiation…
is the stabilizations of both β-… KRAS mutations in colorectal tumorigenesis including initiation…
[HTML][HTML] mTOR cross-talk in cancer and potential for combination therapy
F Conciatori, L Ciuffreda, C Bazzichetto, I Falcone… - Cancers, 2018 - mdpi.com
… signaling, describe its cross-talk with other pathways, and examine its contribution to human
cancer … The AKT/mTOR signaling transduction pathway plays a central role in integrating …
cancer … The AKT/mTOR signaling transduction pathway plays a central role in integrating …
[HTML][HTML] Cross-Talk between the TGF-β and Cell Adhesion Signaling Pathways in Cancer
J Liao, R Chen, B Lin, R Deng, Y Liang… - … Journal of Medical …, 2024 - ncbi.nlm.nih.gov
… signal transduction. CAMs function as transmembrane proteins, the extracellular domain
stabilizes cells to bind to adjacent cells and ECM, while … the migration of colorectal cancer cells …
stabilizes cells to bind to adjacent cells and ECM, while … the migration of colorectal cancer cells …
Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552
J Wang, L Han, J Sinnett-Smith… - … of Physiology-Cell …, 2016 - journals.physiology.org
… used as a model system to examine signal transduction pathways in response to GPCR
activation (… for the function of the pathway in normal and cancer cells is well recognized (22), the …
activation (… for the function of the pathway in normal and cancer cells is well recognized (22), the …
[HTML][HTML] Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression
F He, H Chen, P Yang, Q Wu, T Zhang, C Wang, J Wei… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… Importantly, we found a unique molecular mechanism of Gankyrin in CRC cells signaling
transduction, that regulated the cross-talk between PI3K/Akt and Wnt/β-catenin signaling …
transduction, that regulated the cross-talk between PI3K/Akt and Wnt/β-catenin signaling …
The role of the tumor microenvironment in colorectal cancer and the potential therapeutic approaches
… cross talk between these cells may result in either advantages or disadvantages in tumor
development and metastasis, affecting the signals … Class 1 agents suppress signal transduction …
development and metastasis, affecting the signals … Class 1 agents suppress signal transduction …
[HTML][HTML] RIZ2 at the crossroad of the EGF/EGFR signaling in colorectal cancer
M Di Donato, E Di Zazzo, A Salvati… - Journal of Translational …, 2023 - Springer
… expression control to signal transduction pathways and … cancer cells and tumor-associated
macrophages are involved in a cross-talk that affects and enhances malignancy of colon …
macrophages are involved in a cross-talk that affects and enhances malignancy of colon …
[HTML][HTML] Impact of STAT-signaling pathway on cancer-associated fibroblasts in colorectal cancer and its role in immunosuppression
D Sánchez-Ramírez… - World Journal of …, 2024 - ncbi.nlm.nih.gov
… , in which cancer-… in tumorigenesis through different mechanisms. However, their role in
immunosuppression in CRC is not well understood, and the precise role of signal transducers …
immunosuppression in CRC is not well understood, and the precise role of signal transducers …