… for assembly of such gene transfer system, the potential of modified silica nanoparticles
as a … Silica nanoparticles modified with aminosilanes as carriers for plasmid DNA. Int J …

… Silica-based nanoparticles are promising carriers for gene … was the aminosilanemodified
solid silica nanoparticles with … capacity toward negatively charged plasmid DNA (pDNA) and …

… , but functional modification of the carriers may affect their gene … Plasmid DNA (pEGFP-C1)
in buffer solutions were mixed … was lower than the intrinsic pK a of aminosilane (∼9.8) [47]. It …

… a surface modification with amino-silanes and further … ], few are about silica particles as gene
carriers. One of them … non-porous silica nanoparticles and modified them with amine groups …

… of large molecule therapeutic agents such as plasmid DNA (pDNA) and proteins … Amino
silanes and polycation polymers have been widely used as chemical agents for modifying silica …

… In order to avoid such problems the surface of the nanoparticles was modified with silica,
aminosilane, chitosan and Tris. The use of such capping agents provides stabilization of …

… Mesoporous silica (MPS) is an excellent carrier because of its … amino modification on MCM-41
for adsorption of plasmid DNA (… functionalized by diverse aminosilane coupling reagents. …

… plasmid DNA ranging from 1.0 × 10 5 copies/μL to 1.0 × 10 0 copies/μL were used for the
study. The plasmid DNA … pneumoniae plasmid DNA spiked into pharynx swabs were employed …

… for the synthesis and co-modification of mesoporous silica nanoparticles (MSNs) with various
… silica nanoparticles as controlled release drug delivery and gene transfection carriers. …

… (eg, thermal heating 29 and DNA carriers 30 ) and can provide … nanoparticles to successfully
link with DNA, we modified a … and plasmid DNA modifications in the mesoporous silica shell …