… naturally-occurring single nucleotide polymorphisms (SNPs) … Until 2003, it was thought that
only one isoform of TPH existed… novel mechanistic insight. In vivo, at low concentrations of …

… analyze the haplotype frequencies of these four SNPs instead of considering separate genes.
Three of the four single nucleotide polymorphisms under study … GTAC haplotypes were …

… disorder and these single nucleotide polymorphisms (SNPs), the … TPH1 and TPH2 are
isoforms of TPH. Both … found that in patients with MDD the rs4570625–rs10748185 GA haplotype …

… the serotonin-1A receptor gene single nucleotide polymorphism rs6295C/G and symptoms
of … SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene …

… only one gene encodes TPH, a brain-specific TPH isoform, … G-703T (rs4570625) single
nucleotide polymorphism (SNP), … are numerous single polymorphisms and haplotypes to consider…

… polymorphisms may be theoretically associated with the occurrence and development of LPE,
which could potentially become a novel … database of single nucleotide polymorphism 147, …

… , VNTRs, and alleles of tryptophan hydroxylase (TPH, the rate-… are expected to express
TPH2 isoforms with activity that is … 5-HT 1B receptor haplotypes such as the 3′-untranslated …

… To study TPH1 A779C single nucleotide polymorphism in … TPH gene has two isoforms, ie,
TPH1 and TPH2 [7, 8]. TPH1 … However, in the same study, haplotype analysis suggested that in …

… Haplotypes can be more specific risk markers than single alleles, and … analyzed were in
the same haplotype block, we performed the two–four SNP sliding window haplotype analysis […

… Having performed haplotype and gen-gen analyses, it was … Therefore, single-nucleotide
polymorphisms (SNPs) were … TRYCATs pathway, including tryptophan hydroxylase, kynurenine …