… Single-nucleotide polymorphism arrays (SNP-A) karyotyping … progression to acute myeloid
leukaemia (AML). Diagnosis and … CN-LOH as either the sole abnormality or as a concurrent …

… risk for progression to acute myeloid leukemia. MDS is currently … /total deletions of
chromosomes 5, 7, 13, 20, X/Y or trisomy 8), … cases where adequate karyotype analysis is not …

… with chromosome 8 specific probes and by array-based copy … number analysis with
single-nucleotide polymorphism (SNP)-… in sole trisomy 8 and other karyotypes involving and extra …

… include abnormalities of chromosome 7, trisomy 8 and 21, −… karyotype might lead to an
inadequate estimation of the prognostic risk. Single-nucleotide polymorphism (SNP) array-based …

… (AML) in comparison with conventional karyotyping was assessed … whereas in case S08,
which coexisted with Trisomy 8. As the only … by array-based comparative genomic hybridization. …

… arrays (SNP-A) genotyping, array-based comparative genomic … on chromosome 8 are
overexpressed in AML trisomy 8. … karyotypes and large number of chromosomal abnormalities …

… For these reasons, array-based platforms are now widely used … -wide analysis of single
nucleotide polymorphisms in AML … by visible chromosomal abnormalities in the karyotype. …

… trisomy 8 was identified in nine cases as the sole aberration. … karyotype, five resulted in
a discordant cytogenetic IPSS-R resulting in a downgraded cytogenetic IPSS-R array-based …

… abnormalities (CNAs) is at present performed by karyotype … chromosomal abnormalities.
Cell-based analysis makes … used CMA platforms include single nucleotide polymorphism (SNP) …

… chromosome 5q and 7q, trisomy 8, and complex karyotypes. New genomic technologies have
been developted, like single-nucleotide polymorphism … by array-based karyotyping and/or …