Single-nucleotide polymorphism–based genetic risk score and patient age at prostate cancer diagnosis
Importance Few studies have evaluated the association between a single-nucleotide
polymorphism–based genetic risk score (GRS) and patient age at prostate cancer (PCa)
diagnosis. Objectives To test the association between a GRS and patient age at PCa
diagnosis and to compare the performance of a GRS with that of family history (FH) in PCa
risk stratification. Design, Setting, and Participants A cohort study of 3225 white men was
conducted as a secondary analysis of the Reduction by Dutasteride of Prostate Cancer …
polymorphism–based genetic risk score (GRS) and patient age at prostate cancer (PCa)
diagnosis. Objectives To test the association between a GRS and patient age at PCa
diagnosis and to compare the performance of a GRS with that of family history (FH) in PCa
risk stratification. Design, Setting, and Participants A cohort study of 3225 white men was
conducted as a secondary analysis of the Reduction by Dutasteride of Prostate Cancer …
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