… human cell, although the efficiency of site-specific integration … of the transferred DNA into
DNA sequences of human origin (… role as a site-specific integrase in human cells, which would …

… Inserting custom designed DNA sequences into the … integration of foreign DNA to rapidly
prototype synthetic gene networks in mammalian cells. (88) In this study, site-specific integration …

… Collectively, these integration experiments indicate that leader sequences and host factors
… IHF fold DNA into a structure that is necessary for site-specific integration of foreign DNA into …

… Collectively, these integration experiments indicate that leader sequences and host factors
… IHF fold DNA into a structure that is necessary for site-specific integration of foreign DNA into …

… We define an integration locus as a sequenced integration of a donor cargo … Taken
together, we demonstrate the ability to identify site-specific LSRs by computationally comparing …

… and the site-specific integrase Bxb1 to integrate DNA constructs … kb into mouse zygotes with
germline transmission and into … DNA sequences together with high fidelity, given a minimum …

… site-specific DNA integration via a fused DNA binding domain of Sleeping Beauty transposase
to tether the DNA … sequence can be recruited to the target site and increase transgene …

… showed that foreign DNA can be introduced into human cells … the ability to catalyze site-specific
recombination between two copies … to genetically modify specific human target cells in a …

… Initially, integration of foreign DNA into eukaryotic genomes … advances for site-specific
insertion of relatively large DNA. … for germline site-specific integration, and sequencing the …

… Our aim was high efficiency, site-specific recombination … off-target integration of the donor
attP-GT sequence, we … Although we did not screen for off-target integration, we did find that …