Sleep, cognitive impairment, and Alzheimer's disease: a systematic review and meta-analysis

OM Bubu, M Brannick, J Mortimer, O Umasabor-Bubu… - Sleep, 2017 - academic.oup.com
… , including shorter sleep duration and fragmented sleep, 4–7 … of sleep on cognitive decline
and/or Alzheimer's disease meta-… alterations, nocturnal sleep fragmentation, decreased sleep

Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer's dementia

K Kaneshwaran, M Olah, S Tasaki, L Yu… - Science …, 2019 - science.org
… We assessed sleep fragmentation by actigraphy and related this to cognitive function, to …
Greater sleep fragmentation was associated with higher neocortical expression of genes …

[HTML][HTML] Brain and cognitive correlates of sleep fragmentation in elderly subjects with and without cognitive deficits

C André, C Tomadesso, R de Flores, P Branger… - Alzheimer's & Dementia …, 2019 - Elsevier
… factor for Alzheimer's disease. However, no study has assessed the relationships … in sleep
quality have been related to cognitive decline and increased risk of developing dementia [2], [3…

Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis

W Xu, CC Tan, JJ Zou, XP Cao, L Tan - Journal of Neurology …, 2020 - jnnp.bmj.com
… domains (such as daytime dysfunction, fragmentation, latency and subjective quality). As for
the subtypes of … . Self-Reported sleep disturbance is associated with Alzheimer's disease

Sleep disturbance, cognitive decline, and dementia: a review

AMV Wennberg, MN Wu, PB Rosenberg… - Seminars in …, 2017 - thieme-connect.com
sleep, including sleep fragmentation, abnormal sleep duration, and sleep disorders, as risk
factors for dementia. … —namely Alzheimer's disease (AD) and Parkinson's disease (PD). We …

[HTML][HTML] Fractal regulation and incident Alzheimer's disease in elderly individuals

P Li, L Yu, ASP Lim, AS Buchman, FAJL Scheer… - Alzheimer's & …, 2018 - Elsevier
… and MCI and had a faster cognitive decline. … In the model that includes both sleep
fragmentation index and α, the effect of sleep fragmentation index on incident Alzheimer's dementia

Is sleep disruption a risk factor for Alzheimer's disease?

AC Macedo, S Balouch, N Tabet - … of Alzheimer's Disease, 2017 - content.iospress.com
… with higher levels of sleep fragmentation showed a stronger association of APOE ɛ4 genotype
with cognitive decline, postmortem density of neurofibrillary tangles, and incident AD [32]. …

Advanced circadian timing and sleep fragmentation differentially impact on memory complaint subtype in subjective cognitive decline

JE Manousakis, AJ Scovelle… - … of Alzheimer's …, 2018 - content.iospress.com
… We also show decreased sleep fragmentation and longer total sleep time was associated
with reports of more decline over time, and greater seriousness attributed to everyday memory …

Sleep profile predicts the cognitive decline of mild-moderate Alzheimer's disease patients

ADS Targa, ID Benítez, F Dakterzada, A Carnes… - Sleep, 2021 - academic.oup.com
… to their sleep (one with a propensity to deepen the sleep and … the lighter sleep stage), we
hypothesized that the cognitive decline … In fact, sleep disturbances such as sleep fragmentation, …

Self‐reported sleep fragmentation and sleep duration and their association with cognitive function in PROTECT, a large digital community‐based cohort of people …

JA Aakre, J Schulz, C Ballard, A Corbett… - … Journal of Geriatric …, 2023 - Wiley Online Library
… found no link between insomnia and dementia or Alzheimer's disease. Surprisingly, in the
latter, fragmented sleep was associated with lower dementia risk and better cognition scores. …