Meta-analysis of the associations of CYP2B6-516G> T polymorphisms with efavirenz-induced central nervous system side effects and virological outcome in HIV …
L Cheng, Y Wang, X Li, W Feng, B Weng… - The …, 2020 - nature.com
… the GG genotype was 23.3% (126/541), for the GT genotype was … One study carried out
among a Chinese HIV-infected … , while sleep disturbance is recorded in nearly half of cases, and …
among a Chinese HIV-infected … , while sleep disturbance is recorded in nearly half of cases, and …
Dose optimization of efavirenz based on individual CYP2B6 polymorphisms in Chinese patients positive for HIV
KH Hui, SS Lee, TN Lam - CPT: pharmacometrics & systems …, 2016 - Wiley Online Library
… genotype for each patient was identified as GG, GT, or TT. … data were collected from the
databases of different sources, … a study of the sleep quality of efavirenz-treated patients. Source #…
databases of different sources, … a study of the sleep quality of efavirenz-treated patients. Source #…
Effects of rifampicin, CYP2B6 and ABCB1 polymorphisms on efavirenz plasma concentration in Chinese patients living with HIV and tuberculosis
L Zhang, X Meng, P Dong, T Qi… - … journal of STD & …, 2023 - journals.sagepub.com
… to be lower in patients with 516 GT and 785 GG genotypes in HIV/TB group, … difference
between HIV and HIV/TB groups was not significant in patients with CYP2B6 785 GG genotype…
between HIV and HIV/TB groups was not significant in patients with CYP2B6 785 GG genotype…
Neuropsychiatric manifestations among HIV-1 infected African patients receiving efavirenz-based cART with or without tuberculosis treatment containing rifampicin
S Mugusi, E Ngaimisi, M Janabi, F Mugusi… - European Journal of …, 2018 - Springer
… in the genotype frequencies among the HIV-only patients compared to those with HIV-TB. …
and the reported efavirenz associated sleep disturbances and hallucinations in our patients. …
and the reported efavirenz associated sleep disturbances and hallucinations in our patients. …
Adverse neuropsychiatric events and recreational use of efavirenz and other HIV-1 antiretroviral drugs
… -based treatment is generally well-tolerated in children, although some experience persistent
concentration problems, as well as sleep … Recently emerging associations between HIV-…
concentration problems, as well as sleep … Recently emerging associations between HIV-…
Polymorphisms at CYP enzymes, NR1I2 and NR1I3 in association with virologic response to antiretroviral therapy in Brazilian HIV-positive individuals
C de Almeida Velozo, TB de Almeida… - The …, 2022 - nature.com
… of ART ( adj HR = 0.32 for GG genotype and 0.62 for G carriers) (… All patients from our cohort
received ART regimens that … in Supplementary Table 5 for different biogeographical groups. …
received ART regimens that … in Supplementary Table 5 for different biogeographical groups. …
… of pharmacogenetics determinants of efavirenz response that includes 3′-UTR single nucleotide polymorphisms among Black South African HIV/AIDS patients
… (PXR) were selected for genotyping among 222 Bantu-speaking South African HIV-infected …
for each HIV/AIDS patient and median EFV plasma concentrations were compared between …
for each HIV/AIDS patient and median EFV plasma concentrations were compared between …
Multimodality assessment of sleep outcomes in people living with HIV performed using validated sleep questionnaires
A Milinkovic, S Singh, B Simmons… - … journal of STD & …, 2020 - journals.sagepub.com
… in people living with HIV (PLHIV) report high rates of sleep disturbance, … sleep quality in
PLHIV. We administered eight validated sleep and wellbeing questionnaires, recording different …
PLHIV. We administered eight validated sleep and wellbeing questionnaires, recording different …
Effect of mid-dose efavirenz concentrations and CYP2B6 genotype on viral suppression in patients on first-line antiretroviral therapy
… HIV-RNA and efavirenz mid-dose interval concentrations … (Life Technologies, Beijing, China).
DNA samples were left at … efavirenz concentration dichotomised at different cut-off values. …
DNA samples were left at … efavirenz concentration dichotomised at different cut-off values. …