Plasma soluble glycoprotein VI, platelet function, bleeding, and ischemic events in patients undergoing elective percutaneous coronary intervention

S Lahu, K Adler, K Mayer… - Thrombosis and …, 2024 - thieme-connect.com
… nonlinear relation between plasma levels of soluble glycoprotein VI and the risk of bleeding.
Plasma levels above … with acute ischemic stroke.[31] Another study showed that decreased …

Plasma Soluble Glycoprotein VI: A Biomarker of Bleeding

DJ Schneider - Thrombosis and Haemostasis, 2024 - thieme-connect.com
… In this issue of Thrombosis and Haemostasis, Lahu and colleagues report an association
between soluble glycoprotein VI (sGPVI) and the risk of bleeding.[1] The investigators did not …

Beyond antiplatelets: the role of glycoprotein VI in ischemic stroke

I Induruwa, SM Jung… - … Journal of Stroke, 2016 - journals.sagepub.com
Glycoprotein VI (GPVI) is increasingly being recognized as the main platelet-collagen …
This review summarizes the crucial role GPVI plays in ischemic stroke as well as the current …

Plasma C‐type lectin‐like receptor 2 as a predictor of death and vascular events in patients with acute ischemic stroke

X Wu, W Zhang, H Li, S You, J Shi… - European Journal of …, 2019 - Wiley Online Library
… CLEC-2 uses a similar signalling pathway to glycoprotein VI (… Glycoprotein VI has been
shown to play a crucial role in … and increased GPVI activity in acute ischemic stroke patients 3-5. …

Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results

I Induruwa, H McKinney, C Kempster, P Thomas… - Plos one, 2022 - journals.plos.org
elevated in the plasma of ischemic stroke patients. To reconcile those observations with our
own, we suggest that under the acute stroke conditions of day-0, patientsplateletsplatelets. …

Soluble glycoprotein VI, a specific marker of platelet activation is increased in the plasma of subjects with seropositive rheumatoid arthritis

JR Stack, A Madigan, L Helbert, E Dunne… - PLoS …, 2017 - journals.plos.org
… It is interesting to note that a similar association has been observed between sGPVI and
acute ischaemic stroke. Within this study we retrospectively identified an increased number of …

Glenzocimab: a GPVI (glycoprotein VI)-targeted potential antiplatelet agent for the treatment of acute ischemic stroke

S Wichaiyo, W Parichatikanond, W Rattanavipanon - Stroke, 2022 - Am Heart Assoc
… experiments that platelet GPVI (glycoprotein VI) contributes to thrombosis, particularly in
ischemic stroke. Moreover, GPVI levels are upregulated in stroke patients. This review describes …

Prognostic significance of plasma CLEC-2 (C-type lectin-like receptor 2) in patients with acute ischemic stroke

X Zhang, W Zhang, X Wu, H Li, C Zhang, Z Huang… - Stroke, 2019 - Am Heart Assoc
… pCLEC-2 and ischemic stroke is same as that reported about GP VI and ischemic stroke.
In our present study, an association of pCLEC-2 with stroke progression and prognosis has …

[HTML][HTML] Mechanical circulatory support is associated with loss of platelet receptors glycoprotein Ibα and glycoprotein VI

P Lukito, A Wong, J Jing, JF Arthur, SF Marasco… - Journal of Thrombosis …, 2016 - Elsevier
patients, consistent with AVWS. Platelet receptor shedding was demonstrated by elevated
soluble glycoprotein (GP) VI levels in plasma … CF‐VAD and ECMO patients as compared with …

Atherosclerosis, myocardial infarction and primary hemostasis: Impact of platelets, von Willebrand factor and soluble glycoprotein VI

JM Villmann, R Burkhardt, A Teren, T Villmann… - Thrombosis …, 2019 - Elsevier
… reached in models including acute phase parameters (specificity 0,9036, sensitivity 0,7937
in men; 0,8977 and 0,8133 in women). In detail, hematocrit and soluble glycoprotein VI were …