… between male and female sex-determining genes are required for the bipotential gonads to
… studies demonstrate that the Sry gene evolved from the autosomal Sox3 gene approximately …

… of development of female and male gonads have different … -box (SOX) transcription factors
that play a role in many tissues. … is necessary for meiotic division of germ cells in females [59]. …

… Yet, identification of Sox3 Y indeed proved that any player in … of mouse resulted in
female-to-male sex reversal and the … Further studies are required to determine how Enh13 …

… Here, we review the roles that SOX genes play in gonad … of sex determination and
differentiation, DSDs, and the SOX … of SOX gene expression levels needed for gonad development …

… SRY/Sry—the gene essential for male sex determination. … and DNA target sites identification
of SOX proteins has been … both male and female gonads until the critical sex determining …

… that SRY, which triggers the male sex determination pathway, … SOX3 and SRY genes suggests
that alteration of SOX3 methylation may affect gonadal development in dogs with a female …

… The processes of sex determination and gonadal … There are 20 members of the SOX family
found in mammals, with a well-… are sex reversed is that the SOX9 expression levels required …

… Sox3 gene, whose expression level was high in the gonads … indicate that Sox3 plays a role
in female sex determination by … for the first time that Sox3 may be required for the sex reversal …

… suggest that sox3 might have different functions in male and female … , but was not necessary
for gonad sexual determination in mice. However, sox3 is considered as a male determining …

… genes are also essential for gonadal development in males, … 46,XX male sex reversal,
suggesting that SOX3 can be a … in female gonads. Moreover, overexpression of miR-107 in …