… in the absence of extrinsic depolarizing influences such as … and the effects of
vasospasm-related vasoconstrictor factors … that reduction of K ATP current and K ATP …

… conduction system, ventricles, smooth muscle, endothelium, and … The various subtypes of
K ATP channels originate in part … In another study, the same mutation had no effect on K ATP …

… process in the generation of excessive smooth muscle … loss of KATP activity in the smooth
muscles of the coronary … for lysine and occurs on chromosome 12q24.2, leading to a mutant, …

… from the critical role of K ATP channels in vascular smooth muscle cell function. However, …
SUR2 null mice arose from a coronary artery vascular smooth muscle–extrinsic process. In …

… intracoronary administration of nitroglycerin once CAS occurs [63,64]. … knockout mice,
suggesting that loss of function of KATP channels can induce hypercontraction of smooth muscle …

… pancreatic over the cardiac and smooth muscle KATP channels (… similar smooth muscle cells
from Kir6.2 knockout mice show … in contrast did not have evidence of coronary artery spasm …

… small-conductance KATP channel was identified at the cardiac … mice vascular smooth
muscle cell, coronary arteries smooth … coronary vasospasm and sudden death. The vasculature …

… This phenotype reportedly persists in SUR2 knockout mice … in smooth muscle, suggesting
that vasospasm may arise from … K ATP channels in the Cantu mice in smooth muscle or …

… coronary and brachiocephalic arteries, those that supply the descending thoracic aorta arise
… resulted from the assembly–disassembly processes. These flexible characteristics of the …

… Coronary artery spasm (CAS) is a reversible phenomenon caused by spontaneous excessive
vascular smooth muscle … The loss of KATP activity in the smooth muscles of the coronary …