[HTML][HTML] Exosomes in coronary artery disease

XF Gao, ZM Wang, F Wang, Y Gu… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
… , platelets, cardiomyocytes, and stem cells have been reported to play … to prevent ischemic
myocardium against acute ischemia/… translation of exosomes in the diagnosis and treatment of …

[HTML][HTML] Arming mesenchymal stromal/stem cells against cancer: has the time come?

G Golinelli, I Mastrolia, B Aramini, V Masciale… - Frontiers in …, 2020 - frontiersin.org
therapies to generate an increasing awareness of their potential and limits to accelerate their
clinical translation. … Figure 1 Mesenchymal stromal/stem cells (MSCs) can be functionalized …

Towards clinical translation of FLASH radiotherapy

MC Vozenin, J Bourhis, M Durante - Nature Reviews Clinical Oncology, 2022 - nature.com
… The direct action of radiation on DNA has cytotoxic effects on differentiated, progenitor
and stem cells, followed by indirect stimulation of reactive oxygen species and inflammatory …

Clinical trials with mesenchymal stem cells: an update

T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
… of numerous diseases has been used to address their translation from … for the treatment of
cardiovascular disease represent a … , and use in therapy are standardized toward isolating and …

Mesenchymal stromal cell therapy in bronchopulmonary dysplasia: systematic review and meta-analysis of preclinical studies

S Augustine, MT Avey, B Harrison… - Stem cells …, 2017 - academic.oup.com
… cause of death among children under 5 years of age. Currently, there is no treatment for …
In a first step to ensure the evidence-based translation of this promising MSC therapy into …

Stem cell therapies for acute spinal cord injury in humans: a review

MC Jin, ZA Medress, TD Azad, VM Doulames… - Neurosurgical …, 2019 - thejns.org
… recent advances in stem cell biology and discuss ongoing clinical translation efforts, including
… engraftment, survival, and direct differentiation toward desired cell types after SCI (Fig. 1). …

Gene therapy for metachromatic leukodystrophy

JB Rosenberg, SM Kaminsky… - Journal of …, 2016 - Wiley Online Library
… A therapeutic strategy that could make stem cell therapy a … Hence, most children with severe
forms of MLD would not be … As a next step toward clinical translation, an NHP study was …

[HTML][HTML] Strategies of adoptive T-cell transfer to treat refractory viral infections post allogeneic stem cell transplantation

T Kaeuferle, R Krauss, F Blaeschke, S Willier… - Journal of hematology & …, 2019 - Springer
Translation of this individualized treatment into first-line clinical … of a CAR T cell therapy
against persistent viral infections post … of AdV-specific T cells, nine children with systemic AdV …

Generation of endothelial cells from human pluripotent stem cells: methods, considerations, and applications

IM Williams, JC Wu - Arteriosclerosis, thrombosis, and vascular …, 2019 - Am Heart Assoc
… are not suitable for clinical translation due to the requirement … 4) directs hESC differentiation
toward an HEP fate. HEPs can … angiogenic cell therapy for cardiovascular disease has been …

Regenerative Medicine for the Treatment of Congenital Heart Disease

E Dzilic, S Doppler, R Lange, M Krane - … Regenerative Medicine: Tissue …, 2019 - Springer
… pave the way toward a new area in the management of CHD, … , which bioengineering and
stem cell therapy hope to meet. The … These devices cannot be translated into pediatric patients …