… We sought to compare the efficacy and safety of rivaroxaban … of new prescriptions for oral
anticoagulation in patients with … %) patients, 1678 (27%) received co-therapy with aspirin, and …

… both stroke prevention in non-valvular atrial fibrillation and … of thrombin (dabigatran) or factor
Xa (rivaroxaban, apixaban, … with acetylsalicylic acid alone or with acetylsalicylic acid plus …

… comparisons of direct oral anticoagulants rather than relying … the comparative effectiveness
and cost-effectiveness of … stroke varied by concomitant aspirin use, history of warfarin …

… or the direct oral anticoagulants (DOAC). These include … only studies that evaluated the
relative efficiency of at least two … compared warfarin with DOACs, LAAC, clopidogrel and aspirin, …

… Apixaban, edoxaban, rivaroxaban, and dabigatran reduced the risk of ischemic stroke and
intracranial bleeding compared to warfarin… for NOACs relative to warfarin and aspirin in RCTs …

… ); HTA documents for Germany, France, and Spain reported … comparing NOACs with
vitamin K antagonists or aspirin in an … Cost-effectiveness was a major driver of positive …

… oral anticoagulation is an important topic because of stroke … is also important for cost-effectiveness
models in the context … compare the complications that occurred with Rivaroxaban with …

… -VKA including dabigatran and rivaroxaban (both first introduced in the UK in 2008), apixaban
(… OAC and the risk of stroke if they do not receive OAC when in fact their relative gain from …

… Interestingly, apixaban exhibited a similar profile to aspirin in terms of safety (… , comparing
the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation, …

… to be of significant efficacy compared with aspirin. An individual … (dabigatran, rivaroxaban
and apixaban) versus warfarin … to compare the efficacy, safety and cost effectiveness of DOACs, …